FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1991221605> ?p ?o ?g. }

• W1991221605 endingPage "2506" @default.
• W1991221605 startingPage "2499" @default.
• W1991221605 abstract "We describe the regulation mechanisms of the Na+-dependent neutral amino acid transporter ASCT2 via nitric oxide (NO) in the human intestinal cell line, Caco-2. Exposure of Caco-2 cells to S-nitrosothiol, such as S-nitroso-N-acetyl-dl-penicillamine (SNAP) and S-nitrosoglutathione, and the NO-donor, NOC12, concentration- and time-dependently increased Na+-dependent alanine uptake. Kinetic analyses indicated that SNAP increases the maximal velocity (V max) of Na+-dependent alanine uptake in Caco-2 cells without affecting the Michaelis–Menten constant (K t). The stimulatory effect was partially eliminated by actinomycin D and cycloheximide. Increased Na+-dependent alanine uptake by SNAP was partially abolished by the NO scavengers, 2-(4-carboxyphenyl)-4,4,5,5-tetramethylimidazoline-1-oxyl 3-oxide sodium salt (carboxy-PTIO) and N-(dithiocarboxy)sarcosine disodium salts (DTCS), as well as the NADPH oxidase inhibitor, diphenyleneiodonium. RT-PCR revealed that Caco-2 cells expressed the Na+-dependent neutral amino acid transporter ASCT2, but not the other Na+-dependent neutral amino acid transporters ATB0,+ and B0AT1. These results suggested that functional up-regulation of ASCT2 by SNAP might be partially associated with an increase in the density of transporter protein via de novo synthesis." @default.
• W1991221605 created "2016-06-24" @default.
• W1991221605 creator A5007636706 @default.
• W1991221605 creator A5013295761 @default.
• W1991221605 creator A5019102457 @default.
• W1991221605 creator A5041331842 @default.
• W1991221605 creator A5074500273 @default.
• W1991221605 date "2005-04-07" @default.
• W1991221605 modified "2023-09-26" @default.
• W1991221605 title "Functional regulation of Na⁺-dependent neutral amino acid transporter ASCT2 by<i>S</i>-nitrosothiols and nitric oxide in Caco-2 cells" @default.
• W1991221605 cites W1528545147 @default.
• W1991221605 cites W1560571961 @default.
• W1991221605 cites W1905499293 @default.
• W1991221605 cites W1964103615 @default.
• W1991221605 cites W1967051529 @default.
• W1991221605 cites W1972580189 @default.
• W1991221605 cites W1972600953 @default.
• W1991221605 cites W1973971913 @default.
• W1991221605 cites W1976433941 @default.
• W1991221605 cites W1978752676 @default.
• W1991221605 cites W1982557947 @default.
• W1991221605 cites W1985473430 @default.
• W1991221605 cites W2011964721 @default.
• W1991221605 cites W2018076581 @default.
• W1991221605 cites W2024608964 @default.
• W1991221605 cites W2036140137 @default.
• W1991221605 cites W2040750819 @default.
• W1991221605 cites W2041826465 @default.
• W1991221605 cites W2059281609 @default.
• W1991221605 cites W2060243949 @default.
• W1991221605 cites W2066953042 @default.
• W1991221605 cites W2076670842 @default.
• W1991221605 cites W2081485204 @default.
• W1991221605 cites W2083504073 @default.
• W1991221605 cites W2092574194 @default.
• W1991221605 cites W2094391131 @default.
• W1991221605 cites W2141522397 @default.
• W1991221605 cites W2145806440 @default.
• W1991221605 cites W2186334188 @default.
• W1991221605 cites W2404082640 @default.
• W1991221605 doi "https://doi.org/10.1016/j.febslet.2005.03.065" @default.
• W1991221605 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15848195" @default.
• W1991221605 hasPublicationYear "2005" @default.
• W1991221605 type Work @default.
• W1991221605 sameAs 1991221605 @default.
• W1991221605 citedByCount "28" @default.
• W1991221605 countsByYear W19912216052012 @default.
• W1991221605 countsByYear W19912216052013 @default.
• W1991221605 countsByYear W19912216052014 @default.
• W1991221605 countsByYear W19912216052015 @default.
• W1991221605 countsByYear W19912216052022 @default.
• W1991221605 crossrefType "journal-article" @default.
• W1991221605 hasAuthorship W1991221605A5007636706 @default.
• W1991221605 hasAuthorship W1991221605A5013295761 @default.
• W1991221605 hasAuthorship W1991221605A5019102457 @default.
• W1991221605 hasAuthorship W1991221605A5041331842 @default.
• W1991221605 hasAuthorship W1991221605A5074500273 @default.
• W1991221605 hasBestOaLocation W19912216051 @default.
• W1991221605 hasConcept C104317684 @default.
• W1991221605 hasConcept C118687296 @default.
• W1991221605 hasConcept C120405084 @default.
• W1991221605 hasConcept C121684516 @default.
• W1991221605 hasConcept C12554922 @default.
• W1991221605 hasConcept C149011108 @default.
• W1991221605 hasConcept C178790620 @default.
• W1991221605 hasConcept C185592680 @default.
• W1991221605 hasConcept C2778128677 @default.
• W1991221605 hasConcept C2779840497 @default.
• W1991221605 hasConcept C2779856020 @default.
• W1991221605 hasConcept C2779997099 @default.
• W1991221605 hasConcept C3675279 @default.
• W1991221605 hasConcept C41008148 @default.
• W1991221605 hasConcept C515207424 @default.
• W1991221605 hasConcept C519581460 @default.
• W1991221605 hasConcept C55493867 @default.
• W1991221605 hasConcept C60987743 @default.
• W1991221605 hasConcept C86803240 @default.
• W1991221605 hasConceptScore W1991221605C104317684 @default.
• W1991221605 hasConceptScore W1991221605C118687296 @default.
• W1991221605 hasConceptScore W1991221605C120405084 @default.
• W1991221605 hasConceptScore W1991221605C121684516 @default.
• W1991221605 hasConceptScore W1991221605C12554922 @default.
• W1991221605 hasConceptScore W1991221605C149011108 @default.
• W1991221605 hasConceptScore W1991221605C178790620 @default.
• W1991221605 hasConceptScore W1991221605C185592680 @default.
• W1991221605 hasConceptScore W1991221605C2778128677 @default.
• W1991221605 hasConceptScore W1991221605C2779840497 @default.
• W1991221605 hasConceptScore W1991221605C2779856020 @default.
• W1991221605 hasConceptScore W1991221605C2779997099 @default.
• W1991221605 hasConceptScore W1991221605C3675279 @default.
• W1991221605 hasConceptScore W1991221605C41008148 @default.
• W1991221605 hasConceptScore W1991221605C515207424 @default.
• W1991221605 hasConceptScore W1991221605C519581460 @default.
• W1991221605 hasConceptScore W1991221605C55493867 @default.
• W1991221605 hasConceptScore W1991221605C60987743 @default.
• W1991221605 hasConceptScore W1991221605C86803240 @default.
• W1991221605 hasIssue "11" @default.
• W1991221605 hasLocation W19912216051 @default.

• next