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• W1991231944 abstract "The positional cloning of the hypocretin receptor 2, the gene for autosomal recessive canine narcolepsy, has led to the development of a physical map spanning a large portion of canine chromosome 12 (CFA12), in a region corresponding to human chromosome 6p12-q13. More than 40 expressed sequence tags (ESTs) were used in homology search experiments, together with chromosome walking, to build both physical and radiation hybrid maps of the CFA12 13-21 region. The resulting map of bacterial artificial chromosome ends, ESTs, and microsatellite markers represents the longest continuous high-density map of the dog genome reported to date. These data further establish the dog as a system for studying disease genes of interest to human populations and highlight feasible approaches for positional cloning of disease genes in organisms where genomic resources are limited." @default.
• W1991231944 created "2016-06-24" @default.
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• W1991231944 date "2001-05-01" @default.
• W1991231944 modified "2023-10-02" @default.
• W1991231944 title "Physical and Radiation Hybrid Mapping of Canine Chromosome 12, in a Region Corresponding to Human Chromosome 6p12–q12" @default.
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• W1991231944 doi "https://doi.org/10.1006/geno.2000.6487" @default.
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