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- W1991286144 abstract "Lysophosphatidic acid (LPA) and sphingosine 1-phosphate (S1P) are serum-borne lysophospholipids that signal through their cognate G protein-coupled receptors to evoke a great variety of responses in numerous cell types. In addition to stimulating cell proliferation and survival, LPA and S1P induce profound cytoskeletal changes through Rho-mediated signaling pathways, leading to such diverse responses as cell rounding, neurite retraction, and modulation of tumor cell invasiveness (transcellular migration). A major recent advance is the identification of a subfamily of heptahelical receptors for LPA and S1P." @default.
- W1991286144 created "2016-06-24" @default.
- W1991286144 creator A5061490638 @default.
- W1991286144 date "1999-11-01" @default.
- W1991286144 modified "2023-10-17" @default.
- W1991286144 title "Bioactive Lysophospholipids and Their G Protein-Coupled Receptors" @default.
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- W1991286144 doi "https://doi.org/10.1006/excr.1999.4702" @default.
- W1991286144 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10579925" @default.
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