Matches in SemOpenAlex for { <https://semopenalex.org/work/W1991328198> ?p ?o ?g. }
- W1991328198 endingPage "416" @default.
- W1991328198 startingPage "365" @default.
- W1991328198 abstract "In this review an attempt has been made to compile all the existing comprehensive literature for the synthesis of 1,1-Dimethyl-3-oxobutyl-isothiocyanate (DMO-ITC) and its reactions with the compounds having different functional groups, such as amines, diamines, amino alcohols, amino phenols, amino thiophenols, amino nitriles, amino acids, and hydrazines. The peculiar behavior of the DMO-ITC is due to its sensitivity toward acids and gives different products when the reaction occurs in the absence and presence of an acid. The pH of the reaction condition also plays an important role. Normally, DMO-ITC gives pyrimidinethione derivatives when treated with amines, but reactions become interesting when the compounds have an amino group as well as the other functional group (NH 2 , OH, SH, CN, COOH) at ortho position, providing condensed bicyclic, tricyclic, or poly heterocycles with ring nitrogen and/or sulfur is of biological importance. The reaction of DMO-ITC with ethylene diamine, o -phenylenediamines, 1,2-diaminoanthraquinone, o -diaminonaphthalenes, N -aminoethyladenosine, 2-amino ethanol, o -aminophenols, o -aminothiophenols, o -aminobenzonitriles, and o -aminobenzoic acids gave imidazopyrimidinethione, pyrimidobenzimidazolethiones, pyrimidoanthraquinonimidazolethione, pyrimidonaphthoimidazolethiones, furanopurinimidazopyrimidinethione, oxazolopyrimidinethione, oxafluorenethiones, thiafluorenethiones, thioxophenanthreneones, and thiaphenanthreneones derivatives respectively. But similar reactions were not seen with o -diaminoheterocycles. Hydrazines derivatives gave seven-membered heterocycles, that is, triazepinethiones derivatives. The synthesis of the heterocycles are well defined in separate sections according to the update references." @default.
- W1991328198 created "2016-06-24" @default.
- W1991328198 creator A5006313822 @default.
- W1991328198 date "2003-02-01" @default.
- W1991328198 modified "2023-09-24" @default.
- W1991328198 title "Synthesis and Reactions of 1,1-Dimethyl-3-oxobutyl-isothiocyanate (DMO-ITC)" @default.
- W1991328198 cites W123796011 @default.
- W1991328198 cites W126348045 @default.
- W1991328198 cites W1559339326 @default.
- W1991328198 cites W1596788490 @default.
- W1991328198 cites W1603591561 @default.
- W1991328198 cites W1687796364 @default.
- W1991328198 cites W182847004 @default.
- W1991328198 cites W1940956811 @default.
- W1991328198 cites W1965612247 @default.
- W1991328198 cites W1975365227 @default.
- W1991328198 cites W1977851818 @default.
- W1991328198 cites W1982495792 @default.
- W1991328198 cites W1994818910 @default.
- W1991328198 cites W2000520353 @default.
- W1991328198 cites W2005644558 @default.
- W1991328198 cites W2007535201 @default.
- W1991328198 cites W2008241104 @default.
- W1991328198 cites W2008331177 @default.
- W1991328198 cites W2009921564 @default.
- W1991328198 cites W2011332192 @default.
- W1991328198 cites W2013246614 @default.
- W1991328198 cites W2015400221 @default.
- W1991328198 cites W2016215367 @default.
- W1991328198 cites W2019705482 @default.
- W1991328198 cites W2025604288 @default.
- W1991328198 cites W2025825690 @default.
- W1991328198 cites W2026478760 @default.
- W1991328198 cites W2028016714 @default.
- W1991328198 cites W2032103813 @default.
- W1991328198 cites W2033124658 @default.
- W1991328198 cites W2034426587 @default.
- W1991328198 cites W2036119324 @default.
- W1991328198 cites W2037274129 @default.
- W1991328198 cites W2039709956 @default.
- W1991328198 cites W2040920412 @default.
- W1991328198 cites W2043172711 @default.
- W1991328198 cites W2044382720 @default.
- W1991328198 cites W2049161957 @default.
- W1991328198 cites W2053048430 @default.
- W1991328198 cites W2055476522 @default.
- W1991328198 cites W2064817106 @default.
- W1991328198 cites W2064942496 @default.
- W1991328198 cites W2065066801 @default.
- W1991328198 cites W2068080814 @default.
- W1991328198 cites W2071498550 @default.
- W1991328198 cites W2076429988 @default.
- W1991328198 cites W2084282937 @default.
- W1991328198 cites W2084757828 @default.
- W1991328198 cites W2093499592 @default.
- W1991328198 cites W2101906452 @default.
- W1991328198 cites W2102901903 @default.
- W1991328198 cites W2139334970 @default.
- W1991328198 cites W2166362064 @default.
- W1991328198 cites W225676313 @default.
- W1991328198 cites W226427098 @default.
- W1991328198 cites W2315657816 @default.
- W1991328198 cites W2322670981 @default.
- W1991328198 cites W2323303643 @default.
- W1991328198 cites W2323883871 @default.
- W1991328198 cites W2324371068 @default.
- W1991328198 cites W2330186399 @default.
- W1991328198 cites W2332831319 @default.
- W1991328198 cites W2334513567 @default.
- W1991328198 cites W2335253585 @default.
- W1991328198 cites W2394591035 @default.
- W1991328198 cites W250316850 @default.
- W1991328198 cites W2511321909 @default.
- W1991328198 cites W261888186 @default.
- W1991328198 cites W277123216 @default.
- W1991328198 cites W2949096717 @default.
- W1991328198 cites W2949808408 @default.
- W1991328198 cites W2950004346 @default.
- W1991328198 cites W2950491781 @default.
- W1991328198 cites W2950737069 @default.
- W1991328198 cites W2951124095 @default.
- W1991328198 cites W2951317541 @default.
- W1991328198 cites W2952479742 @default.
- W1991328198 cites W2952742528 @default.
- W1991328198 cites W4229550699 @default.
- W1991328198 cites W4238237801 @default.
- W1991328198 cites W4238284686 @default.
- W1991328198 cites W4241776550 @default.
- W1991328198 cites W4245582392 @default.
- W1991328198 cites W4733733 @default.
- W1991328198 cites W81534005 @default.
- W1991328198 cites W83020924 @default.
- W1991328198 cites W2047083850 @default.
- W1991328198 cites W2317295353 @default.
- W1991328198 doi "https://doi.org/10.1080/10426500307949" @default.
- W1991328198 hasPublicationYear "2003" @default.
- W1991328198 type Work @default.
- W1991328198 sameAs 1991328198 @default.