FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1991332521> ?p ?o ?g. }

• W1991332521 endingPage "768" @default.
• W1991332521 startingPage "761" @default.
• W1991332521 abstract "Previous studies have demonstrated a significant pressure gradient from carotid artery to pial or middle cerebral arteries. This pressure gradient suggests that large cerebral arteries contribute to cerebral resistance. We have tested the hypothesis that large cerebral arteries contribute to regulation of cerebral blood flow during changes in blood gases and arterial pressure. Microspheres were used to measure brain blood flow in anesthetized dogs. Resistance of large cerebral arteries was estimated by determining the pressure gradient between common carotid and wedged vertebral artery catheters. Systemic hypercapnia and hypoxia dilated large cerebral arteries, and hypocapnia constricted large cerebral arteries. Resistance of large arteries was 0.6+/-0.1 (mean +/- SE) mm Hg per ml/min per 100 g during normocapnia. During hypercapnia and hypoxia, large artery resistance decreased significantly to 0.2 +/- 0.03 and 0.3 +/- 0.05, respectively. During hypocapnia large artery resistance increased significantly to 1.0 +/- 0.1. In other experiments, we found that large cerebral arteries participate in auto-regulatory responses to hemorrhagic hypotension. When arterial pressure was reduced from 110 to 58 mm Hg, autoregulation maintained cerebral blood flow constant, and resistance of large cerebral arteries decreased significantly from 1.0 +/- 0.2 to 0.6 +/- 0.1 mm Hg per ml/min per 100 g. In absolute terms, we calculated that 20-45% of the change in total cerebral resistance during these interventions was accounted for by changes in large artery resistance. These studies indicate that large cerebral arteries, as well as arterioles, participate actively in regulation of cerebral blood flow during changes in arterial blood gases and during autoregulatory responses to hemorrhagic hypotension." @default.
• W1991332521 created "2016-06-24" @default.
• W1991332521 creator A5054622637 @default.
• W1991332521 creator A5054771891 @default.
• W1991332521 creator A5091500935 @default.
• W1991332521 date "1978-10-01" @default.
• W1991332521 modified "2023-10-14" @default.
• W1991332521 title "Role of Large Arteries in Regulation of Cerebral Blood Flow in Dogs" @default.
• W1991332521 cites W1915148248 @default.
• W1991332521 cites W1966040669 @default.
• W1991332521 cites W2009621826 @default.
• W1991332521 cites W2018980239 @default.
• W1991332521 cites W2021233767 @default.
• W1991332521 cites W2061735293 @default.
• W1991332521 cites W2072483534 @default.
• W1991332521 cites W2072761121 @default.
• W1991332521 cites W2090929953 @default.
• W1991332521 cites W2109348605 @default.
• W1991332521 cites W2132924014 @default.
• W1991332521 cites W2140656153 @default.
• W1991332521 cites W2162571456 @default.
• W1991332521 cites W2165702652 @default.
• W1991332521 cites W2329305565 @default.
• W1991332521 cites W2338976229 @default.
• W1991332521 cites W2406618640 @default.
• W1991332521 cites W2413872557 @default.
• W1991332521 cites W2418409816 @default.
• W1991332521 cites W2418581357 @default.
• W1991332521 doi "https://doi.org/10.1172/jci109187" @default.
• W1991332521 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/371827" @default.
• W1991332521 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/701475" @default.
• W1991332521 hasPublicationYear "1978" @default.
• W1991332521 type Work @default.
• W1991332521 sameAs 1991332521 @default.
• W1991332521 citedByCount "124" @default.
• W1991332521 countsByYear W19913325212012 @default.
• W1991332521 countsByYear W19913325212013 @default.
• W1991332521 countsByYear W19913325212014 @default.
• W1991332521 countsByYear W19913325212015 @default.
• W1991332521 countsByYear W19913325212016 @default.
• W1991332521 countsByYear W19913325212017 @default.
• W1991332521 countsByYear W19913325212018 @default.
• W1991332521 countsByYear W19913325212019 @default.
• W1991332521 countsByYear W19913325212020 @default.
• W1991332521 countsByYear W19913325212021 @default.
• W1991332521 countsByYear W19913325212022 @default.
• W1991332521 crossrefType "journal-article" @default.
• W1991332521 hasAuthorship W1991332521A5054622637 @default.
• W1991332521 hasAuthorship W1991332521A5054771891 @default.
• W1991332521 hasAuthorship W1991332521A5091500935 @default.
• W1991332521 hasBestOaLocation W19913325211 @default.
• W1991332521 hasConcept C111774379 @default.
• W1991332521 hasConcept C126322002 @default.
• W1991332521 hasConcept C157767197 @default.
• W1991332521 hasConcept C164705383 @default.
• W1991332521 hasConcept C171614378 @default.
• W1991332521 hasConcept C2775841333 @default.
• W1991332521 hasConcept C2776820930 @default.
• W1991332521 hasConcept C2777037550 @default.
• W1991332521 hasConcept C2778553927 @default.
• W1991332521 hasConcept C2778866228 @default.
• W1991332521 hasConcept C2781382112 @default.
• W1991332521 hasConcept C42219234 @default.
• W1991332521 hasConcept C541997718 @default.
• W1991332521 hasConcept C58245268 @default.
• W1991332521 hasConcept C71924100 @default.
• W1991332521 hasConcept C84359808 @default.
• W1991332521 hasConcept C84393581 @default.
• W1991332521 hasConceptScore W1991332521C111774379 @default.
• W1991332521 hasConceptScore W1991332521C126322002 @default.
• W1991332521 hasConceptScore W1991332521C157767197 @default.
• W1991332521 hasConceptScore W1991332521C164705383 @default.
• W1991332521 hasConceptScore W1991332521C171614378 @default.
• W1991332521 hasConceptScore W1991332521C2775841333 @default.
• W1991332521 hasConceptScore W1991332521C2776820930 @default.
• W1991332521 hasConceptScore W1991332521C2777037550 @default.
• W1991332521 hasConceptScore W1991332521C2778553927 @default.
• W1991332521 hasConceptScore W1991332521C2778866228 @default.
• W1991332521 hasConceptScore W1991332521C2781382112 @default.
• W1991332521 hasConceptScore W1991332521C42219234 @default.
• W1991332521 hasConceptScore W1991332521C541997718 @default.
• W1991332521 hasConceptScore W1991332521C58245268 @default.
• W1991332521 hasConceptScore W1991332521C71924100 @default.
• W1991332521 hasConceptScore W1991332521C84359808 @default.
• W1991332521 hasConceptScore W1991332521C84393581 @default.
• W1991332521 hasIssue "4" @default.
• W1991332521 hasLocation W19913325211 @default.
• W1991332521 hasLocation W19913325212 @default.
• W1991332521 hasLocation W19913325213 @default.
• W1991332521 hasLocation W19913325214 @default.
• W1991332521 hasLocation W19913325215 @default.
• W1991332521 hasOpenAccess W1991332521 @default.
• W1991332521 hasPrimaryLocation W19913325211 @default.
• W1991332521 hasRelatedWork W1979841695 @default.
• W1991332521 hasRelatedWork W2043923411 @default.
• W1991332521 hasRelatedWork W2046264635 @default.
• W1991332521 hasRelatedWork W2049058816 @default.
• W1991332521 hasRelatedWork W2067313594 @default.

• next