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• W1991352613 abstract "The structure and interactive properties of liquid-crystalline egg phosphatidylcholine (EPC) bilayers containing the ganglioside GM1 and its uncharged analogue, asialoGM1 (AGM1), have been obtained by X-ray diffraction analysis of osmotically stressed liposomes. Both electron density profiles and reciprocal space modeling indicate that (1) the incorporation of up to 30 mol % GM1 into EPC bilayers has little effect on bilayer organization and (2) the oligosaccharide portion of the GM1 molecule extends at least 12 A beyond the EPC head group into the fluid space, implying that the GM1 head group is nearly fully extended from the bilayer surface. Pressure-distance relations for EPC:GM1 bilayers in 100 mM ionic strength buffer show that, for large bilayer separations, the interbilayer repulsive pressure decays exponentially with a decay length and magnitude expected for electrostatic repulsion arising from the charged GM1. However, at interbilayer separations of < or = 30 A for 7:3 and 8:2 EPC:GM1 and < or = 22 A for 9:1 EPC:GM1, the pressure-distance curves have distinct upward breaks, with the sharpness of this break depending strongly on the amount of GM1 in the bilayer. For 7:3 EPC:GM1 bilayers, the break is quite sharp so that the distance between bilayers does not decrease below 28 A with further increases in applied pressure. For EPC:GM1 8:2 and 9:1 bilayers, the upward break becomes softer with decreasing GM1 concentration. For uncharged EPC:AGM1 bilayers, the repulsive pressure extends only to an equilibrium fluid separation of about 36 A, but has a similar behavior to the pressure-distance data for EPC:GM1 for separations below 20 A. We argue that the nonelectrostatic repulsive pressures arise primarily from the steric interactions between the hydrated oligosaccharide head groups that protrude from the bilayer surface." @default.
• W1991352613 created "2016-06-24" @default.
• W1991352613 creator A5036879055 @default.
• W1991352613 creator A5058526709 @default.
• W1991352613 date "1994-08-30" @default.
• W1991352613 modified "2023-09-30" @default.
• W1991352613 title "Long- and Short-Range Interactions between Phospholipid/Ganglioside GM1 Bilayers" @default.
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• W1991352613 cites W1555141533 @default.
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• W1991352613 cites W1589158676 @default.
• W1991352613 cites W1668613150 @default.
• W1991352613 cites W1963722000 @default.
• W1991352613 cites W1967838912 @default.
• W1991352613 cites W1969359430 @default.
• W1991352613 cites W1969661949 @default.
• W1991352613 cites W1972936661 @default.
• W1991352613 cites W1975941955 @default.
• W1991352613 cites W1979577349 @default.
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• W1991352613 cites W1985737470 @default.
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• W1991352613 cites W2024389606 @default.
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• W1991352613 cites W2056169846 @default.
• W1991352613 cites W2056566990 @default.
• W1991352613 cites W2056876953 @default.
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• W1991352613 doi "https://doi.org/10.1021/bi00200a032" @default.
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