FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1991372004> ?p ?o ?g. }

• W1991372004 endingPage "356" @default.
• W1991372004 startingPage "335" @default.
• W1991372004 abstract "Field potentials produced by antidromic invasion of Purkyně cells in the decerebrate cat were used in studying the action of a parallel fiber volley on Purkyně cells, both in the unanesthetized and the anesthetized cerebellum. The standard procedures of microelectrode recording and of stimulating by concentric electrodes were employed. A high level of discrimination was made possible by very fast sweep recording of antidromic field potentials that were conditioned by the parallel fiber volleys at a wide range of test intervals (up to 500 msec) and observed at all depths through the cerebellar cortex. It was confirmed that in the unanesthetized cerebellum a parallel fiber volley often effected a facilitation of the antidromic spike potential at test intervals of 10–50 msec, or at the least there was a facilitatory influence causing a delayed onset of inhibition. There was evidence that this facilitation is due to an excitatory action on the Purkyně cells that enhanced the antidromic invasion of the large dendrites. However, longer test intervals, 100 up to 500 msec, disclosed a large inhibitory action, which may be attributed to basket cells just as in the anesthetized cerebellum. Even in light anesthesia facilitation of dendritic invasion was eliminated, and excitatory synaptic action on the dendrites no longer prevented cell inhibition from blocking axon-soma transmission in many Purkyně cells; hence the observed inhibition of the antidromic field potentials even at brief test intervals. All gradations of this dominance of inhibition over excitation were observed as anesthesia was increased. With very deep anesthesia there was abolition of the inhibitory action, which presumably is due to depression of the inhibitory interneurons. As a final stage the depth profile of the antidromic potentials indicated that there is even blockage of axon-soma transmission of all Purkyně cells. It is concluded that the unanesthetized cerebellum differs from the anesthetized because there is a higher level of excitability of Purkyně cells. As a consequence the excitatory action of the parallel fiber synapses tends to dominate over the inhibitory action of the basket cells. There is no necessity to postulate, as Bloedel and Roberts have done, that in the unanesthetizes cerebellum there is a fundamental difference in the processing of information." @default.
• W1991372004 created "2016-06-24" @default.
• W1991372004 creator A5049121411 @default.
• W1991372004 creator A5050858786 @default.
• W1991372004 creator A5084729298 @default.
• W1991372004 date "1971-01-01" @default.
• W1991372004 modified "2023-09-23" @default.
• W1991372004 title "The action of a parallel fiber volley on the antidromic invasion of Purkyně cells of cat cerebellum" @default.
• W1991372004 cites W1190408229 @default.
• W1991372004 cites W1972329131 @default.
• W1991372004 cites W1975712914 @default.
• W1991372004 cites W1984999105 @default.
• W1991372004 cites W2000783781 @default.
• W1991372004 cites W2010776579 @default.
• W1991372004 cites W2017650531 @default.
• W1991372004 cites W2058433520 @default.
• W1991372004 cites W2085975593 @default.
• W1991372004 cites W2097386801 @default.
• W1991372004 cites W2104321133 @default.
• W1991372004 cites W2301339089 @default.
• W1991372004 cites W2394891067 @default.
• W1991372004 doi "https://doi.org/10.1016/0006-8993(71)90442-2" @default.
• W1991372004 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/5545723" @default.
• W1991372004 hasPublicationYear "1971" @default.
• W1991372004 type Work @default.
• W1991372004 sameAs 1991372004 @default.
• W1991372004 citedByCount "49" @default.
• W1991372004 countsByYear W19913720042012 @default.
• W1991372004 countsByYear W19913720042016 @default.
• W1991372004 countsByYear W19913720042022 @default.
• W1991372004 crossrefType "journal-article" @default.
• W1991372004 hasAuthorship W1991372004A5049121411 @default.
• W1991372004 hasAuthorship W1991372004A5050858786 @default.
• W1991372004 hasAuthorship W1991372004A5084729298 @default.
• W1991372004 hasConcept C112592302 @default.
• W1991372004 hasConcept C169760540 @default.
• W1991372004 hasConcept C17077164 @default.
• W1991372004 hasConcept C185263204 @default.
• W1991372004 hasConcept C185592680 @default.
• W1991372004 hasConcept C19071747 @default.
• W1991372004 hasConcept C2779530196 @default.
• W1991372004 hasConcept C2779652256 @default.
• W1991372004 hasConcept C70471684 @default.
• W1991372004 hasConcept C86803240 @default.
• W1991372004 hasConceptScore W1991372004C112592302 @default.
• W1991372004 hasConceptScore W1991372004C169760540 @default.
• W1991372004 hasConceptScore W1991372004C17077164 @default.
• W1991372004 hasConceptScore W1991372004C185263204 @default.
• W1991372004 hasConceptScore W1991372004C185592680 @default.
• W1991372004 hasConceptScore W1991372004C19071747 @default.
• W1991372004 hasConceptScore W1991372004C2779530196 @default.
• W1991372004 hasConceptScore W1991372004C2779652256 @default.
• W1991372004 hasConceptScore W1991372004C70471684 @default.
• W1991372004 hasConceptScore W1991372004C86803240 @default.
• W1991372004 hasIssue "2" @default.
• W1991372004 hasLocation W19913720041 @default.
• W1991372004 hasLocation W19913720042 @default.
• W1991372004 hasOpenAccess W1991372004 @default.
• W1991372004 hasPrimaryLocation W19913720041 @default.
• W1991372004 hasRelatedWork W1973430209 @default.
• W1991372004 hasRelatedWork W1982195338 @default.
• W1991372004 hasRelatedWork W2015147756 @default.
• W1991372004 hasRelatedWork W2124878846 @default.
• W1991372004 hasRelatedWork W2153693073 @default.
• W1991372004 hasRelatedWork W2160512273 @default.
• W1991372004 hasRelatedWork W2335861766 @default.
• W1991372004 hasRelatedWork W2471120693 @default.
• W1991372004 hasRelatedWork W2911853463 @default.
• W1991372004 hasRelatedWork W3209986146 @default.
• W1991372004 hasVolume "25" @default.
• W1991372004 isParatext "false" @default.
• W1991372004 isRetracted "false" @default.
• W1991372004 magId "1991372004" @default.
• W1991372004 workType "article" @default.