Matches in SemOpenAlex for { <https://semopenalex.org/work/W1991373417> ?p ?o ?g. }
- W1991373417 endingPage "2837" @default.
- W1991373417 startingPage "2833" @default.
- W1991373417 abstract "The transposon TnphoA was used to generate fusions between phoA, the gene for alkaline phosphatase (PhoA), and genes encoding proteins that are secreted by Vibrio cholerae. One of the PhoA+ mutants isolated showed a dramatic reduction in its ability to colonize the intestines of suckling mice. This mutant no longer produced a 20.5-kDa protein (TcpA) that we show is the major subunit of a V. cholerae pilus. Amino-terminal sequence analysis of the TcpA pilus subunit showed that it shares amino acid homology with the pilins produced by several other pathogenic bacteria. The TcpA pilus was coordinately expressed with cholera toxin under various culture conditions, and this effect appeared to be dependent on the transcriptional activator encoded by the toxR gene. We conclude that the toxR gene plays a central role in the transcriptional regulation of multiple virulence genes of V. cholerae." @default.
- W1991373417 created "2016-06-24" @default.
- W1991373417 creator A5001002482 @default.
- W1991373417 creator A5033034795 @default.
- W1991373417 creator A5045253972 @default.
- W1991373417 creator A5047063103 @default.
- W1991373417 date "1987-05-01" @default.
- W1991373417 modified "2023-10-10" @default.
- W1991373417 title "Use of phoA gene fusions to identify a pilus colonization factor coordinately regulated with cholera toxin." @default.
- W1991373417 cites W1481326951 @default.
- W1991373417 cites W1755468429 @default.
- W1991373417 cites W1826534722 @default.
- W1991373417 cites W1843386821 @default.
- W1991373417 cites W1878688220 @default.
- W1991373417 cites W1943831286 @default.
- W1991373417 cites W1947850442 @default.
- W1991373417 cites W1995445964 @default.
- W1991373417 cites W2001304636 @default.
- W1991373417 cites W2018015451 @default.
- W1991373417 cites W2036366956 @default.
- W1991373417 cites W2047119945 @default.
- W1991373417 cites W2051774198 @default.
- W1991373417 cites W2055600356 @default.
- W1991373417 cites W2063450941 @default.
- W1991373417 cites W2095448507 @default.
- W1991373417 cites W2104371757 @default.
- W1991373417 cites W2140890315 @default.
- W1991373417 cites W2143256722 @default.
- W1991373417 cites W2143328033 @default.
- W1991373417 cites W2171866359 @default.
- W1991373417 doi "https://doi.org/10.1073/pnas.84.9.2833" @default.
- W1991373417 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/304754" @default.
- W1991373417 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2883655" @default.
- W1991373417 hasPublicationYear "1987" @default.
- W1991373417 type Work @default.
- W1991373417 sameAs 1991373417 @default.
- W1991373417 citedByCount "939" @default.
- W1991373417 countsByYear W19913734172012 @default.
- W1991373417 countsByYear W19913734172013 @default.
- W1991373417 countsByYear W19913734172014 @default.
- W1991373417 countsByYear W19913734172015 @default.
- W1991373417 countsByYear W19913734172016 @default.
- W1991373417 countsByYear W19913734172017 @default.
- W1991373417 countsByYear W19913734172018 @default.
- W1991373417 countsByYear W19913734172019 @default.
- W1991373417 countsByYear W19913734172020 @default.
- W1991373417 countsByYear W19913734172021 @default.
- W1991373417 countsByYear W19913734172022 @default.
- W1991373417 countsByYear W19913734172023 @default.
- W1991373417 crossrefType "journal-article" @default.
- W1991373417 hasAuthorship W1991373417A5001002482 @default.
- W1991373417 hasAuthorship W1991373417A5033034795 @default.
- W1991373417 hasAuthorship W1991373417A5045253972 @default.
- W1991373417 hasAuthorship W1991373417A5047063103 @default.
- W1991373417 hasBestOaLocation W19913734171 @default.
- W1991373417 hasConcept C104292427 @default.
- W1991373417 hasConcept C104317684 @default.
- W1991373417 hasConcept C143065580 @default.
- W1991373417 hasConcept C174832134 @default.
- W1991373417 hasConcept C2777006276 @default.
- W1991373417 hasConcept C2778643871 @default.
- W1991373417 hasConcept C523546767 @default.
- W1991373417 hasConcept C54355233 @default.
- W1991373417 hasConcept C60987743 @default.
- W1991373417 hasConcept C86803240 @default.
- W1991373417 hasConcept C89423630 @default.
- W1991373417 hasConceptScore W1991373417C104292427 @default.
- W1991373417 hasConceptScore W1991373417C104317684 @default.
- W1991373417 hasConceptScore W1991373417C143065580 @default.
- W1991373417 hasConceptScore W1991373417C174832134 @default.
- W1991373417 hasConceptScore W1991373417C2777006276 @default.
- W1991373417 hasConceptScore W1991373417C2778643871 @default.
- W1991373417 hasConceptScore W1991373417C523546767 @default.
- W1991373417 hasConceptScore W1991373417C54355233 @default.
- W1991373417 hasConceptScore W1991373417C60987743 @default.
- W1991373417 hasConceptScore W1991373417C86803240 @default.
- W1991373417 hasConceptScore W1991373417C89423630 @default.
- W1991373417 hasIssue "9" @default.
- W1991373417 hasLocation W19913734171 @default.
- W1991373417 hasLocation W19913734172 @default.
- W1991373417 hasLocation W19913734173 @default.
- W1991373417 hasLocation W19913734174 @default.
- W1991373417 hasOpenAccess W1991373417 @default.
- W1991373417 hasPrimaryLocation W19913734171 @default.
- W1991373417 hasRelatedWork W1548133190 @default.
- W1991373417 hasRelatedWork W1630611681 @default.
- W1991373417 hasRelatedWork W1758049144 @default.
- W1991373417 hasRelatedWork W1999713555 @default.
- W1991373417 hasRelatedWork W2030738655 @default.
- W1991373417 hasRelatedWork W2041114904 @default.
- W1991373417 hasRelatedWork W2068811528 @default.
- W1991373417 hasRelatedWork W2089129210 @default.
- W1991373417 hasRelatedWork W2140388770 @default.
- W1991373417 hasRelatedWork W3030874125 @default.
- W1991373417 hasVolume "84" @default.
- W1991373417 isParatext "false" @default.
- W1991373417 isRetracted "false" @default.
- W1991373417 magId "1991373417" @default.