FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1991422018> ?p ?o ?g. }

• W1991422018 endingPage "914" @default.
• W1991422018 startingPage "910" @default.
• W1991422018 abstract "Tumor proliferation, drug resistance and cell stemness are major difficulties that are encountered during breast cancer therapy and are often responsible for disease progression and cancer‑related mortality. β‑catenin is considered to be an invasion gene in breast cancer. However, how β‑catenin regulates breast cancer cell proliferation and stemness remains unclear. In the present study, β‑catenin knockdown by small interfering RNA in MDA‑MB‑468, a highly metastatic breast cancer cell line, inhibited the expression of β‑catenin, Oct3/4 (stemness), survivin (anti‑apoptosis) and BCRP (drug resistance). Knockdown of β‑catenin enhanced the effects of fluorouracil (5‑FU) chemotherapy on the proliferation of MDA‑MB‑468 cells. Thus, these preliminary results indicate that β‑catenin knockdown enhanced 5‑FU‑induced proliferation inhibition in the breast cancer cell line MDA‑MB‑468, and indicate that combining 5‑FU with gene silencing could be an advantageous option for enhancing the curative effect of chemotherapy in breast cancer and other malignancies." @default.
• W1991422018 created "2016-06-24" @default.
• W1991422018 creator A5001049578 @default.
• W1991422018 creator A5003999045 @default.
• W1991422018 creator A5036273991 @default.
• W1991422018 creator A5064044098 @default.
• W1991422018 creator A5068109067 @default.
• W1991422018 date "2014-08-26" @default.
• W1991422018 modified "2023-10-01" @default.
• W1991422018 title "β-catenin knockdown enhances the effects of fluorouracil in the breast cancer cell line MDA-MB-468" @default.
• W1991422018 cites W1775749144 @default.
• W1991422018 cites W1964081206 @default.
• W1991422018 cites W1972372574 @default.
• W1991422018 cites W1975992482 @default.
• W1991422018 cites W2022233074 @default.
• W1991422018 cites W2022717756 @default.
• W1991422018 cites W2023116564 @default.
• W1991422018 cites W2033559279 @default.
• W1991422018 cites W2045066549 @default.
• W1991422018 cites W2045477445 @default.
• W1991422018 cites W2048040344 @default.
• W1991422018 cites W2062069198 @default.
• W1991422018 cites W2065417289 @default.
• W1991422018 cites W2074605890 @default.
• W1991422018 cites W2075219223 @default.
• W1991422018 cites W2077269764 @default.
• W1991422018 cites W2080232352 @default.
• W1991422018 cites W2103288147 @default.
• W1991422018 cites W2115792588 @default.
• W1991422018 cites W2125519401 @default.
• W1991422018 cites W2155507705 @default.
• W1991422018 cites W2158627893 @default.
• W1991422018 cites W2163292580 @default.
• W1991422018 cites W74964901 @default.
• W1991422018 doi "https://doi.org/10.3892/br.2014.353" @default.
• W1991422018 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4179739" @default.
• W1991422018 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25279168" @default.
• W1991422018 hasPublicationYear "2014" @default.
• W1991422018 type Work @default.
• W1991422018 sameAs 1991422018 @default.
• W1991422018 citedByCount "4" @default.
• W1991422018 countsByYear W19914220182015 @default.
• W1991422018 countsByYear W19914220182016 @default.
• W1991422018 countsByYear W19914220182021 @default.
• W1991422018 crossrefType "journal-article" @default.
• W1991422018 hasAuthorship W1991422018A5001049578 @default.
• W1991422018 hasAuthorship W1991422018A5003999045 @default.
• W1991422018 hasAuthorship W1991422018A5036273991 @default.
• W1991422018 hasAuthorship W1991422018A5064044098 @default.
• W1991422018 hasAuthorship W1991422018A5068109067 @default.
• W1991422018 hasBestOaLocation W19914220181 @default.
• W1991422018 hasConcept C104317684 @default.
• W1991422018 hasConcept C119056186 @default.
• W1991422018 hasConcept C121608353 @default.
• W1991422018 hasConcept C126322002 @default.
• W1991422018 hasConcept C137620995 @default.
• W1991422018 hasConcept C143998085 @default.
• W1991422018 hasConcept C173396325 @default.
• W1991422018 hasConcept C190283241 @default.
• W1991422018 hasConcept C2775975398 @default.
• W1991422018 hasConcept C2781018059 @default.
• W1991422018 hasConcept C29537977 @default.
• W1991422018 hasConcept C30145163 @default.
• W1991422018 hasConcept C502942594 @default.
• W1991422018 hasConcept C530470458 @default.
• W1991422018 hasConcept C54355233 @default.
• W1991422018 hasConcept C55493867 @default.
• W1991422018 hasConcept C62112901 @default.
• W1991422018 hasConcept C62478195 @default.
• W1991422018 hasConcept C71924100 @default.
• W1991422018 hasConcept C86803240 @default.
• W1991422018 hasConcept C95444343 @default.
• W1991422018 hasConceptScore W1991422018C104317684 @default.
• W1991422018 hasConceptScore W1991422018C119056186 @default.
• W1991422018 hasConceptScore W1991422018C121608353 @default.
• W1991422018 hasConceptScore W1991422018C126322002 @default.
• W1991422018 hasConceptScore W1991422018C137620995 @default.
• W1991422018 hasConceptScore W1991422018C143998085 @default.
• W1991422018 hasConceptScore W1991422018C173396325 @default.
• W1991422018 hasConceptScore W1991422018C190283241 @default.
• W1991422018 hasConceptScore W1991422018C2775975398 @default.
• W1991422018 hasConceptScore W1991422018C2781018059 @default.
• W1991422018 hasConceptScore W1991422018C29537977 @default.
• W1991422018 hasConceptScore W1991422018C30145163 @default.
• W1991422018 hasConceptScore W1991422018C502942594 @default.
• W1991422018 hasConceptScore W1991422018C530470458 @default.
• W1991422018 hasConceptScore W1991422018C54355233 @default.
• W1991422018 hasConceptScore W1991422018C55493867 @default.
• W1991422018 hasConceptScore W1991422018C62112901 @default.
• W1991422018 hasConceptScore W1991422018C62478195 @default.
• W1991422018 hasConceptScore W1991422018C71924100 @default.
• W1991422018 hasConceptScore W1991422018C86803240 @default.
• W1991422018 hasConceptScore W1991422018C95444343 @default.
• W1991422018 hasIssue "6" @default.
• W1991422018 hasLocation W19914220181 @default.
• W1991422018 hasLocation W19914220182 @default.
• W1991422018 hasLocation W19914220183 @default.
• W1991422018 hasLocation W19914220184 @default.

• next