Matches in SemOpenAlex for { <https://semopenalex.org/work/W1991427144> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W1991427144 endingPage "1399" @default.
- W1991427144 startingPage "1387" @default.
- W1991427144 abstract "To study the influence of the ubiquitous cap structure of nuclear pre-mRNAs on the assembly of a functional splicing complex, the in vitro splicing of a truncated human metallothionein pre-mRNA was examined in the presence of the cap analogue m7GTP. Significant inhibition of splicing was observed at a concentration as low as 5 microM m7GTP. Analysis of the splicing reaction on glycerol density gradients showed two complexes sedimenting at 45S and 22S. When the reaction was carried out in presence of m7GTP a marked decrease of the material sedimenting at 45S, representing the active splicing complex, was observed. When capped pre-mRNA was replaced by uncapped pre-mRNA, complex formation was significantly reduced. These data indicate that the cap structure plays an important yet unknown role in the assembly of spliceosomes." @default.
- W1991427144 created "2016-06-24" @default.
- W1991427144 creator A5029312136 @default.
- W1991427144 creator A5057573151 @default.
- W1991427144 creator A5057812063 @default.
- W1991427144 creator A5064632985 @default.
- W1991427144 creator A5069123810 @default.
- W1991427144 date "1987-01-01" @default.
- W1991427144 modified "2023-10-09" @default.
- W1991427144 title "Assembly of pre-mRNA splicing complex is cap dependent" @default.
- W1991427144 cites W1605480781 @default.
- W1991427144 cites W1968322556 @default.
- W1991427144 cites W1970367879 @default.
- W1991427144 cites W1975642325 @default.
- W1991427144 cites W1980299957 @default.
- W1991427144 cites W1981587090 @default.
- W1991427144 cites W1993243592 @default.
- W1991427144 cites W2003693245 @default.
- W1991427144 cites W2008422577 @default.
- W1991427144 cites W2021054898 @default.
- W1991427144 cites W2039749338 @default.
- W1991427144 cites W2043756613 @default.
- W1991427144 cites W2052745709 @default.
- W1991427144 cites W2065104935 @default.
- W1991427144 cites W2074404295 @default.
- W1991427144 cites W2074427164 @default.
- W1991427144 cites W2075362101 @default.
- W1991427144 cites W2078119356 @default.
- W1991427144 cites W2088259533 @default.
- W1991427144 cites W2125959590 @default.
- W1991427144 doi "https://doi.org/10.1093/nar/15.4.1387" @default.
- W1991427144 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/340556" @default.
- W1991427144 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3644239" @default.
- W1991427144 hasPublicationYear "1987" @default.
- W1991427144 type Work @default.
- W1991427144 sameAs 1991427144 @default.
- W1991427144 citedByCount "52" @default.
- W1991427144 countsByYear W19914271442013 @default.
- W1991427144 countsByYear W19914271442015 @default.
- W1991427144 countsByYear W19914271442016 @default.
- W1991427144 countsByYear W19914271442020 @default.
- W1991427144 crossrefType "journal-article" @default.
- W1991427144 hasAuthorship W1991427144A5029312136 @default.
- W1991427144 hasAuthorship W1991427144A5057573151 @default.
- W1991427144 hasAuthorship W1991427144A5057812063 @default.
- W1991427144 hasAuthorship W1991427144A5064632985 @default.
- W1991427144 hasAuthorship W1991427144A5069123810 @default.
- W1991427144 hasBestOaLocation W19914271442 @default.
- W1991427144 hasConcept C102063271 @default.
- W1991427144 hasConcept C104317684 @default.
- W1991427144 hasConcept C105580179 @default.
- W1991427144 hasConcept C153911025 @default.
- W1991427144 hasConcept C194583182 @default.
- W1991427144 hasConcept C40000846 @default.
- W1991427144 hasConcept C54355233 @default.
- W1991427144 hasConcept C54458228 @default.
- W1991427144 hasConcept C67705224 @default.
- W1991427144 hasConcept C69551769 @default.
- W1991427144 hasConcept C72994624 @default.
- W1991427144 hasConcept C86803240 @default.
- W1991427144 hasConcept C95444343 @default.
- W1991427144 hasConceptScore W1991427144C102063271 @default.
- W1991427144 hasConceptScore W1991427144C104317684 @default.
- W1991427144 hasConceptScore W1991427144C105580179 @default.
- W1991427144 hasConceptScore W1991427144C153911025 @default.
- W1991427144 hasConceptScore W1991427144C194583182 @default.
- W1991427144 hasConceptScore W1991427144C40000846 @default.
- W1991427144 hasConceptScore W1991427144C54355233 @default.
- W1991427144 hasConceptScore W1991427144C54458228 @default.
- W1991427144 hasConceptScore W1991427144C67705224 @default.
- W1991427144 hasConceptScore W1991427144C69551769 @default.
- W1991427144 hasConceptScore W1991427144C72994624 @default.
- W1991427144 hasConceptScore W1991427144C86803240 @default.
- W1991427144 hasConceptScore W1991427144C95444343 @default.
- W1991427144 hasIssue "4" @default.
- W1991427144 hasLocation W19914271441 @default.
- W1991427144 hasLocation W19914271442 @default.
- W1991427144 hasLocation W19914271443 @default.
- W1991427144 hasLocation W19914271444 @default.
- W1991427144 hasOpenAccess W1991427144 @default.
- W1991427144 hasPrimaryLocation W19914271441 @default.
- W1991427144 hasRelatedWork W190398512 @default.
- W1991427144 hasRelatedWork W1979193042 @default.
- W1991427144 hasRelatedWork W2044297968 @default.
- W1991427144 hasRelatedWork W2116178342 @default.
- W1991427144 hasRelatedWork W2119430300 @default.
- W1991427144 hasRelatedWork W2151062280 @default.
- W1991427144 hasRelatedWork W2157980687 @default.
- W1991427144 hasRelatedWork W2160299305 @default.
- W1991427144 hasRelatedWork W4231845790 @default.
- W1991427144 hasRelatedWork W4322832280 @default.
- W1991427144 hasVolume "15" @default.
- W1991427144 isParatext "false" @default.
- W1991427144 isRetracted "false" @default.
- W1991427144 magId "1991427144" @default.
- W1991427144 workType "article" @default.