Matches in SemOpenAlex for { <https://semopenalex.org/work/W1991444213> ?p ?o ?g. }
Showing items 1 to 84 of
84
with 100 items per page.
- W1991444213 endingPage "367" @default.
- W1991444213 startingPage "363" @default.
- W1991444213 abstract "To determine whether hyperglycemia in brain-dead donors is a sign of endocrine pancreas insufficiency, we studied pancreatic function in 25 consecutive brain dead patients. Blood samples were drawn at 2-hr intervals from donor referral until organ procurement to analyze glucose, insulin, and C-peptide levels. After donor retrieval, two specimens were taken from the pancreas for a subsequent immunohistochemical examination. At referral mean glycemia was 13.60±1.49 mmol/L, and there was a large range of plasma glucose levels (4–6–31.6). Of 25 patients, 16 had glycemia above 10 mmol/L. At organ procurement a mean of 20 hr later, mean glycemia as 8.61±0.58 mmol/L (P<0.005 with paired t test), and only 5 patients had glycemia above 10 mmol/L. Hyperglycemia was associated with elevated insulin and C-peptide levels during donor management. An elevated C-peptide/glucose molar ratio might be considered a sign of peripheral insulin resistance. Hyperglycemia above 25 mmol/L could not be related to the amount of glucose administered during donor maintenance. Severe hyperglycemia had a natural tendency to be partly corrected. Histologic and immunohistochemical examinations were available in 17 cases and can be considered normal. It is concluded that endocrine pancreatic function can be considered effective after brain death. The mechanism of the relative insulin resistance of these patients requires further study. Blood glucose levels, in the range observed in this study, are not a good donor criterion of endocrine pancreatic function before pancreas transplantation." @default.
- W1991444213 created "2016-06-24" @default.
- W1991444213 creator A5015906759 @default.
- W1991444213 creator A5024071753 @default.
- W1991444213 creator A5050224543 @default.
- W1991444213 creator A5053336776 @default.
- W1991444213 creator A5065206007 @default.
- W1991444213 creator A5067499515 @default.
- W1991444213 creator A5079735713 @default.
- W1991444213 date "1993-08-01" @default.
- W1991444213 modified "2023-10-17" @default.
- W1991444213 title "THE ENDOCRINE PANCREAS IN BRAIN-DEAD DONORS A PROSPECTIVE STUDY IN 25 PATIENTS" @default.
- W1991444213 doi "https://doi.org/10.1097/00007890-199308000-00022" @default.
- W1991444213 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8356592" @default.
- W1991444213 hasPublicationYear "1993" @default.
- W1991444213 type Work @default.
- W1991444213 sameAs 1991444213 @default.
- W1991444213 citedByCount "66" @default.
- W1991444213 countsByYear W19914442132012 @default.
- W1991444213 countsByYear W19914442132013 @default.
- W1991444213 countsByYear W19914442132014 @default.
- W1991444213 countsByYear W19914442132016 @default.
- W1991444213 countsByYear W19914442132018 @default.
- W1991444213 countsByYear W19914442132019 @default.
- W1991444213 countsByYear W19914442132020 @default.
- W1991444213 countsByYear W19914442132021 @default.
- W1991444213 countsByYear W19914442132022 @default.
- W1991444213 countsByYear W19914442132023 @default.
- W1991444213 crossrefType "journal-article" @default.
- W1991444213 hasAuthorship W1991444213A5015906759 @default.
- W1991444213 hasAuthorship W1991444213A5024071753 @default.
- W1991444213 hasAuthorship W1991444213A5050224543 @default.
- W1991444213 hasAuthorship W1991444213A5053336776 @default.
- W1991444213 hasAuthorship W1991444213A5065206007 @default.
- W1991444213 hasAuthorship W1991444213A5067499515 @default.
- W1991444213 hasAuthorship W1991444213A5079735713 @default.
- W1991444213 hasBestOaLocation W19914442131 @default.
- W1991444213 hasConcept C126322002 @default.
- W1991444213 hasConcept C134018914 @default.
- W1991444213 hasConcept C165220095 @default.
- W1991444213 hasConcept C2777391703 @default.
- W1991444213 hasConcept C2778764654 @default.
- W1991444213 hasConcept C2778875212 @default.
- W1991444213 hasConcept C2779306644 @default.
- W1991444213 hasConcept C46699223 @default.
- W1991444213 hasConcept C555293320 @default.
- W1991444213 hasConcept C71315377 @default.
- W1991444213 hasConcept C71924100 @default.
- W1991444213 hasConcept C90924648 @default.
- W1991444213 hasConceptScore W1991444213C126322002 @default.
- W1991444213 hasConceptScore W1991444213C134018914 @default.
- W1991444213 hasConceptScore W1991444213C165220095 @default.
- W1991444213 hasConceptScore W1991444213C2777391703 @default.
- W1991444213 hasConceptScore W1991444213C2778764654 @default.
- W1991444213 hasConceptScore W1991444213C2778875212 @default.
- W1991444213 hasConceptScore W1991444213C2779306644 @default.
- W1991444213 hasConceptScore W1991444213C46699223 @default.
- W1991444213 hasConceptScore W1991444213C555293320 @default.
- W1991444213 hasConceptScore W1991444213C71315377 @default.
- W1991444213 hasConceptScore W1991444213C71924100 @default.
- W1991444213 hasConceptScore W1991444213C90924648 @default.
- W1991444213 hasIssue "2" @default.
- W1991444213 hasLocation W19914442131 @default.
- W1991444213 hasLocation W19914442132 @default.
- W1991444213 hasLocation W19914442133 @default.
- W1991444213 hasOpenAccess W1991444213 @default.
- W1991444213 hasPrimaryLocation W19914442131 @default.
- W1991444213 hasRelatedWork W138803513 @default.
- W1991444213 hasRelatedWork W1973049774 @default.
- W1991444213 hasRelatedWork W1986132654 @default.
- W1991444213 hasRelatedWork W1998091002 @default.
- W1991444213 hasRelatedWork W2010140898 @default.
- W1991444213 hasRelatedWork W2031301348 @default.
- W1991444213 hasRelatedWork W2064538767 @default.
- W1991444213 hasRelatedWork W2069827981 @default.
- W1991444213 hasRelatedWork W2082140668 @default.
- W1991444213 hasRelatedWork W4234612679 @default.
- W1991444213 hasVolume "56" @default.
- W1991444213 isParatext "false" @default.
- W1991444213 isRetracted "false" @default.
- W1991444213 magId "1991444213" @default.
- W1991444213 workType "article" @default.