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- W1991452927 abstract "Cell membranes contain small domains (on the order of nanometers in size, sometimes called rafts) of lipids whose hydrocarbon chains are more ordered than those of the surrounding bulk-phase lipids. Whether these domains are fluctuations, metastable, or thermodynamically stable, is still unclear. Here, we show theoretically how a lipid with one saturated hydrocarbon chain that prefers the ordered environment and one partially unsaturated chain that prefers the less ordered phase, can act as a line-active component. We present a unified model that treats the lipids in both the bulk and at the interface and show how they lower the line tension between domains, eventually driving it to zero at sufficiently large interaction strengths or at sufficiently low temperatures. In this limit, finite-sized domains stabilized by the packing of these hybrid lipids can form as equilibrium structures." @default.
- W1991452927 created "2016-06-24" @default.
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- W1991452927 creator A5063734456 @default.
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- W1991452927 date "2009-08-01" @default.
- W1991452927 modified "2023-09-27" @default.
- W1991452927 title "Hybrid Lipids as a Biological Surface-Active Component" @default.
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- W1991452927 doi "https://doi.org/10.1016/j.bpj.2009.05.051" @default.
- W1991452927 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2726333" @default.
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