FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1991454048> ?p ?o ?g. }

• W1991454048 abstract "The membrane mucin MUC1 is altered in its pattern of expression in cancer, and also in other pathological situations, including Helicobacter pylori gastritis. Here we investigate the basis for the loss of apical staining of the gastric foveolar epithelium in H. pylori gastritis.MUC1 was examined in the gastric antrum from cases of H. pylori gastritis and normal controls. We used tissue sections that were either treated or not treated with periodate to effect deglycosylation, and the monoclonal antibodies LICRLonM8, MUSE-11, CT2 and BC2.We show that the epitopes on the TR domain of MUC1 are partially cryptic due to glycosylation and that MUC1 is present on the apical surface of the gastric foveolar epithelium of gastritis patients.This observation suggests that there is no substantial loss of the mucin domain of MUC1 from the apical surface in gastritis, as suggested by others, but rather the H. pylori influences the glycosylation of MUC1. This paper highlights the issue of epitope specificity of monoclonal antibodies directed against disease-associated markers, specifically when they are glycoproteins, as is the case for many cancer markers." @default.
• W1991454048 created "2016-06-24" @default.
• W1991454048 creator A5021425642 @default.
• W1991454048 creator A5031675171 @default.
• W1991454048 creator A5032712853 @default.
• W1991454048 creator A5045327103 @default.
• W1991454048 creator A5066537961 @default.
• W1991454048 creator A5091106436 @default.
• W1991454048 date "2013-02-14" @default.
• W1991454048 modified "2023-10-07" @default.
• W1991454048 title "Apical MUC1 expression revealed on the foveolar epithelium in H. pylori gastritis" @default.
• W1991454048 cites W1603009641 @default.
• W1991454048 cites W1630752783 @default.
• W1991454048 cites W1931951478 @default.
• W1991454048 cites W1964416059 @default.
• W1991454048 cites W1971200885 @default.
• W1991454048 cites W1987180566 @default.
• W1991454048 cites W1989084057 @default.
• W1991454048 cites W1989900776 @default.
• W1991454048 cites W1996054826 @default.
• W1991454048 cites W1996344455 @default.
• W1991454048 cites W2005815854 @default.
• W1991454048 cites W2006212806 @default.
• W1991454048 cites W2008547371 @default.
• W1991454048 cites W2016956014 @default.
• W1991454048 cites W2026407856 @default.
• W1991454048 cites W2029647337 @default.
• W1991454048 cites W2034371209 @default.
• W1991454048 cites W2052541899 @default.
• W1991454048 cites W2062503200 @default.
• W1991454048 cites W2070640326 @default.
• W1991454048 cites W2081268598 @default.
• W1991454048 cites W2083102452 @default.
• W1991454048 cites W2090512053 @default.
• W1991454048 cites W2107939935 @default.
• W1991454048 cites W2126500509 @default.
• W1991454048 cites W2415088729 @default.
• W1991454048 cites W2948387191 @default.
• W1991454048 cites W4211022161 @default.
• W1991454048 doi "https://doi.org/10.1038/bjc.2013.54" @default.
• W1991454048 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3619071" @default.
• W1991454048 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23412104" @default.
• W1991454048 hasPublicationYear "2013" @default.
• W1991454048 type Work @default.
• W1991454048 sameAs 1991454048 @default.
• W1991454048 citedByCount "4" @default.
• W1991454048 countsByYear W19914540482014 @default.
• W1991454048 countsByYear W19914540482015 @default.
• W1991454048 countsByYear W19914540482018 @default.
• W1991454048 countsByYear W19914540482020 @default.
• W1991454048 crossrefType "journal-article" @default.
• W1991454048 hasAuthorship W1991454048A5021425642 @default.
• W1991454048 hasAuthorship W1991454048A5031675171 @default.
• W1991454048 hasAuthorship W1991454048A5032712853 @default.
• W1991454048 hasAuthorship W1991454048A5045327103 @default.
• W1991454048 hasAuthorship W1991454048A5066537961 @default.
• W1991454048 hasAuthorship W1991454048A5091106436 @default.
• W1991454048 hasBestOaLocation W19914540481 @default.
• W1991454048 hasConcept C153911025 @default.
• W1991454048 hasConcept C203014093 @default.
• W1991454048 hasConcept C204232928 @default.
• W1991454048 hasConcept C2776409635 @default.
• W1991454048 hasConcept C2777421810 @default.
• W1991454048 hasConcept C2779422922 @default.
• W1991454048 hasConcept C2781443798 @default.
• W1991454048 hasConcept C3018436504 @default.
• W1991454048 hasConcept C502942594 @default.
• W1991454048 hasConcept C529295009 @default.
• W1991454048 hasConcept C54355233 @default.
• W1991454048 hasConcept C55493867 @default.
• W1991454048 hasConcept C86803240 @default.
• W1991454048 hasConcept C90378955 @default.
• W1991454048 hasConceptScore W1991454048C153911025 @default.
• W1991454048 hasConceptScore W1991454048C203014093 @default.
• W1991454048 hasConceptScore W1991454048C204232928 @default.
• W1991454048 hasConceptScore W1991454048C2776409635 @default.
• W1991454048 hasConceptScore W1991454048C2777421810 @default.
• W1991454048 hasConceptScore W1991454048C2779422922 @default.
• W1991454048 hasConceptScore W1991454048C2781443798 @default.
• W1991454048 hasConceptScore W1991454048C3018436504 @default.
• W1991454048 hasConceptScore W1991454048C502942594 @default.
• W1991454048 hasConceptScore W1991454048C529295009 @default.
• W1991454048 hasConceptScore W1991454048C54355233 @default.
• W1991454048 hasConceptScore W1991454048C55493867 @default.
• W1991454048 hasConceptScore W1991454048C86803240 @default.
• W1991454048 hasConceptScore W1991454048C90378955 @default.
• W1991454048 hasLocation W19914540481 @default.
• W1991454048 hasLocation W19914540482 @default.
• W1991454048 hasLocation W19914540483 @default.
• W1991454048 hasLocation W19914540484 @default.
• W1991454048 hasOpenAccess W1991454048 @default.
• W1991454048 hasPrimaryLocation W19914540481 @default.
• W1991454048 hasRelatedWork W1530072545 @default.
• W1991454048 hasRelatedWork W1531709347 @default.
• W1991454048 hasRelatedWork W167784085 @default.
• W1991454048 hasRelatedWork W1973836804 @default.
• W1991454048 hasRelatedWork W1980850307 @default.
• W1991454048 hasRelatedWork W1986655292 @default.
• W1991454048 hasRelatedWork W1993380004 @default.
• W1991454048 hasRelatedWork W2012403833 @default.

• next