FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1991469098> ?p ?o ?g. }

• W1991469098 endingPage "282" @default.
• W1991469098 startingPage "273" @default.
• W1991469098 abstract "Abstract We examined the changes in phospholipid metabolisms in sodium butyrate‐treated C6 glioma cells. Treatment of 2.5 mM sodium butyrate for 24 h induced an increase in the activity of glutamine synthetase, suggesting that these cells were under differentiation. Similar treatment was associated with (i) increased arachidonic acid incorporation into phosphatidylcholine, and (ii) decreased arachidonic acid incorporation into phosphatidylinositol and (iii) phosphatidylethanolamine. These effects were subsequently investigated by examining the acylation process, de novo biosynthesis, and the agonist‐stimulated phosphoinositides hydrolysis in these cells. Our results indicated that sodium butyrate stimulated the acylation of arachidonic acid into lysophosphatidylcholine, lysophosphatidylethanolamine, and lysophosphatidylinositol. The glycerol incorporation into these lipids was not affected, but the inositol incorporation into these lipids was not affected, but the inositol incorporation into total chloroform extracts and Pl and phosphatidylinositol 4‐phosphate was decreased in the sodium butyrate‐treated cells. Moreover, the accumulation of the rapid histamine‐stimulated phosphoinositide metabolites, i.e., inositol monophosphate, inositol diphosphate, and inositol triphosphate (IP 3 ) was decreased in these cells. To elucidate whether the decreased inositol phosphates were due to a decrease in the phosphoinositides hydrolysis, we measured the transient IP 3 production directly by a receptor‐binding assay. Our results indicated that histamine‐stimulated transient IP 3 formations were decreased. Taken together, these results indicated that multiple changes by multiple mechanisms of phospholipid metabolisms were found in sodium butyrate‐treated C6 glioma cells. The decreased IP 3 formation and its subsequent action, i.e., Ca 2+ mobilization, may play an early but pivotal role by which sodium butyrate induces C6 glioma cell differentiation." @default.
• W1991469098 created "2016-06-24" @default.
• W1991469098 creator A5008910259 @default.
• W1991469098 creator A5034937501 @default.
• W1991469098 creator A5043664524 @default.
• W1991469098 creator A5070464025 @default.
• W1991469098 creator A5077877329 @default.
• W1991469098 date "1997-03-01" @default.
• W1991469098 modified "2023-10-15" @default.
• W1991469098 title "Altered phospholipid metabolism in sodium butyrate‐induced differentiation of C6 glioma cells" @default.
• W1991469098 cites W1775749144 @default.
• W1991469098 cites W1883029873 @default.
• W1991469098 cites W1964344107 @default.
• W1991469098 cites W1972754545 @default.
• W1991469098 cites W1980125393 @default.
• W1991469098 cites W1983030082 @default.
• W1991469098 cites W1997093700 @default.
• W1991469098 cites W1997439964 @default.
• W1991469098 cites W2001949458 @default.
• W1991469098 cites W2006289773 @default.
• W1991469098 cites W2007355372 @default.
• W1991469098 cites W2010324872 @default.
• W1991469098 cites W2010564134 @default.
• W1991469098 cites W2018989647 @default.
• W1991469098 cites W2022692782 @default.
• W1991469098 cites W2023776979 @default.
• W1991469098 cites W2024019570 @default.
• W1991469098 cites W2029210883 @default.
• W1991469098 cites W2039703062 @default.
• W1991469098 cites W2045209911 @default.
• W1991469098 cites W2047176931 @default.
• W1991469098 cites W2057842092 @default.
• W1991469098 cites W2078766701 @default.
• W1991469098 cites W2082209466 @default.
• W1991469098 cites W2100805638 @default.
• W1991469098 cites W2113529592 @default.
• W1991469098 cites W2148534291 @default.
• W1991469098 cites W2238525991 @default.
• W1991469098 cites W2438950707 @default.
• W1991469098 doi "https://doi.org/10.1007/s11745-997-0034-z" @default.
• W1991469098 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9076664" @default.
• W1991469098 hasPublicationYear "1997" @default.
• W1991469098 type Work @default.
• W1991469098 sameAs 1991469098 @default.
• W1991469098 citedByCount "10" @default.
• W1991469098 countsByYear W19914690982015 @default.
• W1991469098 countsByYear W19914690982016 @default.
• W1991469098 countsByYear W19914690982020 @default.
• W1991469098 crossrefType "journal-article" @default.
• W1991469098 hasAuthorship W1991469098A5008910259 @default.
• W1991469098 hasAuthorship W1991469098A5034937501 @default.
• W1991469098 hasAuthorship W1991469098A5043664524 @default.
• W1991469098 hasAuthorship W1991469098A5070464025 @default.
• W1991469098 hasAuthorship W1991469098A5077877329 @default.
• W1991469098 hasConcept C104317684 @default.
• W1991469098 hasConcept C170493617 @default.
• W1991469098 hasConcept C181199279 @default.
• W1991469098 hasConcept C185592680 @default.
• W1991469098 hasConcept C2776330855 @default.
• W1991469098 hasConcept C2777427919 @default.
• W1991469098 hasConcept C2778078955 @default.
• W1991469098 hasConcept C2778918659 @default.
• W1991469098 hasConcept C2778942008 @default.
• W1991469098 hasConcept C2780610907 @default.
• W1991469098 hasConcept C2781112429 @default.
• W1991469098 hasConcept C2781170229 @default.
• W1991469098 hasConcept C41625074 @default.
• W1991469098 hasConcept C55493867 @default.
• W1991469098 hasConcept C62478195 @default.
• W1991469098 hasConceptScore W1991469098C104317684 @default.
• W1991469098 hasConceptScore W1991469098C170493617 @default.
• W1991469098 hasConceptScore W1991469098C181199279 @default.
• W1991469098 hasConceptScore W1991469098C185592680 @default.
• W1991469098 hasConceptScore W1991469098C2776330855 @default.
• W1991469098 hasConceptScore W1991469098C2777427919 @default.
• W1991469098 hasConceptScore W1991469098C2778078955 @default.
• W1991469098 hasConceptScore W1991469098C2778918659 @default.
• W1991469098 hasConceptScore W1991469098C2778942008 @default.
• W1991469098 hasConceptScore W1991469098C2780610907 @default.
• W1991469098 hasConceptScore W1991469098C2781112429 @default.
• W1991469098 hasConceptScore W1991469098C2781170229 @default.
• W1991469098 hasConceptScore W1991469098C41625074 @default.
• W1991469098 hasConceptScore W1991469098C55493867 @default.
• W1991469098 hasConceptScore W1991469098C62478195 @default.
• W1991469098 hasIssue "3" @default.
• W1991469098 hasLocation W19914690981 @default.
• W1991469098 hasLocation W19914690982 @default.
• W1991469098 hasOpenAccess W1991469098 @default.
• W1991469098 hasPrimaryLocation W19914690981 @default.
• W1991469098 hasRelatedWork W1853172101 @default.
• W1991469098 hasRelatedWork W1975586815 @default.
• W1991469098 hasRelatedWork W1990982908 @default.
• W1991469098 hasRelatedWork W2030217219 @default.
• W1991469098 hasRelatedWork W2032212690 @default.
• W1991469098 hasRelatedWork W2049143942 @default.
• W1991469098 hasRelatedWork W2058428082 @default.
• W1991469098 hasRelatedWork W2085692332 @default.
• W1991469098 hasRelatedWork W2265011503 @default.

• next