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- W1991472145 abstract "Coxiella burnetii strains Nine Mile and Priscilla, considered to be associated with acute and chronic forms of Q fever, were investigated for variation in composition of their lipopolysaccharides. Though SDS-PAGE profiles of the lipopolysaccharides were distinct, chemical analyses showed only small differences in their overall composition. Further studies on lipid A-deprived O-polysaccharide fractions of both lipopolysaccharides, obtained by steric-exclusion chromatography, revealed noticeable differences in distribution and chemical composition of the O-polysaccharide chains. It is likely that C. burnetii strains are capable of synthesizing chemically distinct subclasses of O-specific polysaccharide molecules differing in their antigenic reactivities. The results provide suggestive evidence that virulence of C. burnetii may be modulated through lipopolysaccharide composition and structure." @default.
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- W1991472145 date "1998-03-01" @default.
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- W1991472145 title "A comparative study of lipopolysaccharides from two Coxiella burnetii strains considered to be associated with acute and chronic Q fever" @default.
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- W1991472145 doi "https://doi.org/10.1016/s0144-8617(97)00246-4" @default.
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