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- W1991547904 abstract "Background The ATP-binding cassette transporter P-glycoprotein (P-gp) is expressed at the blood-brain barrier (BBB) where it protects the brain from toxic substances and xenobiotics by active efflux transport. The C-labelled third-generation P-gp inhibitor [C]elacridar was developed as a positron emission tomography (PET) tracer for the in vivo quantification of P-gp expression levels in different organs. The aim of this study was to provide human dosimetry estimates for [C]elacridar based on whole-body PET." @default.
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- W1991547904 date "2011-09-05" @default.
- W1991547904 modified "2023-09-26" @default.
- W1991547904 title "[11C]Elacridar as a novel P-glycoprotein PET tracer, assessment of whole-body distribution and radiation dosimetry in humans" @default.
- W1991547904 doi "https://doi.org/10.1186/1471-2210-11-s2-a46" @default.
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