FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1991558426> ?p ?o ?g. }

• W1991558426 endingPage "340" @default.
• W1991558426 startingPage "331" @default.
• W1991558426 abstract "Conjugates between bovine serum albumin and (R,S)-2-aminonicotine were produced, and these conjugates were employed in rabbits and goats for the production of nicotine antibodies. In the assay of nicotine, an 1251-tyrosine methyl ester derivative of (R, S)-6-aminonicotine was employed as radioligand. The antibody-bound derivative was separated from the free derivative by charcoal adsorption (0.5% charcoal, 0.1% dextran T-70, 0.1% bovine serum albumin, pH 7.3). Among the twenty five nicotine derivatives and metabolites examined, (R, S)-6-aminonicotine gave the highest cross-reaction. Cross-reaction with cotinine, a major mammalian metabolite of nicotine, was less than 0.1% for both the rabbit-derived and goat-derived antisera. Cross-reaction by other metabolites, such as (S)-nicotine-n′-oxide, (S)-nornicotine, and N-methylpyrrolidine was less than 1%. The antibodies produced were thus highly specific to nicotine. The radioimmunoassay for nicotine showed a maximum sensitivity of 10 ng/ml in 5O-μl plasma samples for both antisera. After the smoking of a single cigarette (1.2 mg nicotine content in mainstream) the peak blood plasma level nicotine in the subjects varied from 20 – 104 ng/ml, and high levels of nicotine were not necessarily found in heavy smokers." @default.
• W1991558426 created "2016-06-24" @default.
• W1991558426 creator A5008222083 @default.
• W1991558426 creator A5028888302 @default.
• W1991558426 creator A5029653546 @default.
• W1991558426 creator A5050028321 @default.
• W1991558426 creator A5060914335 @default.
• W1991558426 creator A5084170131 @default.
• W1991558426 date "1980-03-01" @default.
• W1991558426 modified "2023-10-12" @default.
• W1991558426 title "Nicotine Antibodies: Comparison of Ligand Specificities of Antibodies Produced against Two Nicotine Conjugates" @default.
• W1991558426 cites W1564405046 @default.
• W1991558426 cites W1599318842 @default.
• W1991558426 cites W1979722407 @default.
• W1991558426 cites W1981399097 @default.
• W1991558426 cites W1981808761 @default.
• W1991558426 cites W1986201372 @default.
• W1991558426 cites W1991714673 @default.
• W1991558426 cites W1998601349 @default.
• W1991558426 cites W2000923313 @default.
• W1991558426 cites W2005711664 @default.
• W1991558426 cites W2015437149 @default.
• W1991558426 cites W202598535 @default.
• W1991558426 cites W2028517190 @default.
• W1991558426 cites W2030006170 @default.
• W1991558426 cites W2033785962 @default.
• W1991558426 cites W2033817042 @default.
• W1991558426 cites W2051597719 @default.
• W1991558426 cites W2062583226 @default.
• W1991558426 cites W2067420198 @default.
• W1991558426 cites W2076815939 @default.
• W1991558426 cites W2081093779 @default.
• W1991558426 cites W2085455597 @default.
• W1991558426 cites W2091588376 @default.
• W1991558426 cites W2134465240 @default.
• W1991558426 cites W2171680377 @default.
• W1991558426 cites W2413358352 @default.
• W1991558426 doi "https://doi.org/10.1111/j.1432-1033.1980.tb04433.x" @default.
• W1991558426 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7189150" @default.
• W1991558426 hasPublicationYear "1980" @default.
• W1991558426 type Work @default.
• W1991558426 sameAs 1991558426 @default.
• W1991558426 citedByCount "19" @default.
• W1991558426 countsByYear W19915584262012 @default.
• W1991558426 countsByYear W19915584262014 @default.
• W1991558426 countsByYear W19915584262015 @default.
• W1991558426 countsByYear W19915584262022 @default.
• W1991558426 crossrefType "journal-article" @default.
• W1991558426 hasAuthorship W1991558426A5008222083 @default.
• W1991558426 hasAuthorship W1991558426A5028888302 @default.
• W1991558426 hasAuthorship W1991558426A5029653546 @default.
• W1991558426 hasAuthorship W1991558426A5050028321 @default.
• W1991558426 hasAuthorship W1991558426A5060914335 @default.
• W1991558426 hasAuthorship W1991558426A5084170131 @default.
• W1991558426 hasBestOaLocation W19915584261 @default.
• W1991558426 hasConcept C126322002 @default.
• W1991558426 hasConcept C159654299 @default.
• W1991558426 hasConcept C176685330 @default.
• W1991558426 hasConcept C185592680 @default.
• W1991558426 hasConcept C203014093 @default.
• W1991558426 hasConcept C2776166849 @default.
• W1991558426 hasConcept C2776319443 @default.
• W1991558426 hasConcept C2777477808 @default.
• W1991558426 hasConcept C2777667214 @default.
• W1991558426 hasConcept C2779547902 @default.
• W1991558426 hasConcept C29144244 @default.
• W1991558426 hasConcept C43617362 @default.
• W1991558426 hasConcept C55493867 @default.
• W1991558426 hasConcept C71240020 @default.
• W1991558426 hasConcept C71924100 @default.
• W1991558426 hasConcept C86803240 @default.
• W1991558426 hasConcept C86807702 @default.
• W1991558426 hasConcept C91523082 @default.
• W1991558426 hasConceptScore W1991558426C126322002 @default.
• W1991558426 hasConceptScore W1991558426C159654299 @default.
• W1991558426 hasConceptScore W1991558426C176685330 @default.
• W1991558426 hasConceptScore W1991558426C185592680 @default.
• W1991558426 hasConceptScore W1991558426C203014093 @default.
• W1991558426 hasConceptScore W1991558426C2776166849 @default.
• W1991558426 hasConceptScore W1991558426C2776319443 @default.
• W1991558426 hasConceptScore W1991558426C2777477808 @default.
• W1991558426 hasConceptScore W1991558426C2777667214 @default.
• W1991558426 hasConceptScore W1991558426C2779547902 @default.
• W1991558426 hasConceptScore W1991558426C29144244 @default.
• W1991558426 hasConceptScore W1991558426C43617362 @default.
• W1991558426 hasConceptScore W1991558426C55493867 @default.
• W1991558426 hasConceptScore W1991558426C71240020 @default.
• W1991558426 hasConceptScore W1991558426C71924100 @default.
• W1991558426 hasConceptScore W1991558426C86803240 @default.
• W1991558426 hasConceptScore W1991558426C86807702 @default.
• W1991558426 hasConceptScore W1991558426C91523082 @default.
• W1991558426 hasIssue "2" @default.
• W1991558426 hasLocation W19915584261 @default.
• W1991558426 hasLocation W19915584262 @default.
• W1991558426 hasOpenAccess W1991558426 @default.
• W1991558426 hasPrimaryLocation W19915584261 @default.
• W1991558426 hasRelatedWork W1829537511 @default.
• W1991558426 hasRelatedWork W1967816828 @default.

• next