Matches in SemOpenAlex for { <https://semopenalex.org/work/W1991566352> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W1991566352 endingPage "450" @default.
- W1991566352 startingPage "447" @default.
- W1991566352 abstract "Different proportions of IgG subclasses have previously been reported to distinguish the immune response elicited by primary and recurrent viral infections, as well as viral vaccines. The goal of this study was to study the IgG subclasses composition in the immune response of patients with Argentine hemorrhagic fever, and vaccinees with Candid #1 strain of Junin virus. Twenty-four individuals inoculated with Candid #1 vaccine and 67 patients with Argentine hemorrhagic fever were studied. Blood samples were drawn at 30, 60, and/or 180 days post-inoculation with Candid #1 and 30, 60, and 90 days after clinical onset of the disease. Specific anti-Junin virus IgG subclasses were titrated with specific human monoclonal antibody fluorescence isothiocyanate conjugate (FITC) by immunofluorescent assay (IFA). IgG1 anti-Junin virus was found in every subject studied and IgG3 was also detected in some patients with a severe form of Argentine hemorrhagic fever. IgG2 and IgG4 were not detected in any serum sample studied. The mean titer of specific IgG1 in vaccinees was significantly lower than in patients with Argentine hemorrhagic fever (P < 0.05), but no difference was found between mild and severe cases of the disease (P > 0.05). The results of this study demonstrated a central role of IgG1 in human recovery from infection with every strain of Junin virus, an observation stressed by the immune response to Candid #1 vaccine, which resulted in no difference in IgG subclasses composition from that found in mild cases of Argentine hemorrhagic fever. J. Med. Virol. 69:447–450, 2003. © 2003 Wiley-Liss, Inc." @default.
- W1991566352 created "2016-06-24" @default.
- W1991566352 creator A5042015965 @default.
- W1991566352 creator A5043753137 @default.
- W1991566352 creator A5082943642 @default.
- W1991566352 creator A5083115057 @default.
- W1991566352 date "2003-01-13" @default.
- W1991566352 modified "2023-10-18" @default.
- W1991566352 title "IgG subclasses in human immune response to wild and attenuated (vaccine) Junin virus infection" @default.
- W1991566352 cites W1573953248 @default.
- W1991566352 cites W1598631917 @default.
- W1991566352 cites W1826181374 @default.
- W1991566352 cites W1885601830 @default.
- W1991566352 cites W1977944577 @default.
- W1991566352 cites W1995183471 @default.
- W1991566352 cites W2001752918 @default.
- W1991566352 cites W2013423878 @default.
- W1991566352 cites W2013908645 @default.
- W1991566352 cites W2015536518 @default.
- W1991566352 cites W2039459437 @default.
- W1991566352 cites W2049808212 @default.
- W1991566352 cites W2073235083 @default.
- W1991566352 cites W2086854330 @default.
- W1991566352 cites W2096735235 @default.
- W1991566352 cites W2148440555 @default.
- W1991566352 cites W2151759979 @default.
- W1991566352 cites W2334749992 @default.
- W1991566352 doi "https://doi.org/10.1002/jmv.10308" @default.
- W1991566352 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12526057" @default.
- W1991566352 hasPublicationYear "2003" @default.
- W1991566352 type Work @default.
- W1991566352 sameAs 1991566352 @default.
- W1991566352 citedByCount "9" @default.
- W1991566352 countsByYear W19915663522018 @default.
- W1991566352 countsByYear W19915663522019 @default.
- W1991566352 countsByYear W19915663522022 @default.
- W1991566352 crossrefType "journal-article" @default.
- W1991566352 hasAuthorship W1991566352A5042015965 @default.
- W1991566352 hasAuthorship W1991566352A5043753137 @default.
- W1991566352 hasAuthorship W1991566352A5082943642 @default.
- W1991566352 hasAuthorship W1991566352A5083115057 @default.
- W1991566352 hasConcept C159047783 @default.
- W1991566352 hasConcept C159654299 @default.
- W1991566352 hasConcept C167672396 @default.
- W1991566352 hasConcept C203014093 @default.
- W1991566352 hasConcept C2522874641 @default.
- W1991566352 hasConcept C2775955205 @default.
- W1991566352 hasConcept C2779574689 @default.
- W1991566352 hasConcept C2780190958 @default.
- W1991566352 hasConcept C32611913 @default.
- W1991566352 hasConcept C542903549 @default.
- W1991566352 hasConcept C71924100 @default.
- W1991566352 hasConcept C86803240 @default.
- W1991566352 hasConcept C8891405 @default.
- W1991566352 hasConceptScore W1991566352C159047783 @default.
- W1991566352 hasConceptScore W1991566352C159654299 @default.
- W1991566352 hasConceptScore W1991566352C167672396 @default.
- W1991566352 hasConceptScore W1991566352C203014093 @default.
- W1991566352 hasConceptScore W1991566352C2522874641 @default.
- W1991566352 hasConceptScore W1991566352C2775955205 @default.
- W1991566352 hasConceptScore W1991566352C2779574689 @default.
- W1991566352 hasConceptScore W1991566352C2780190958 @default.
- W1991566352 hasConceptScore W1991566352C32611913 @default.
- W1991566352 hasConceptScore W1991566352C542903549 @default.
- W1991566352 hasConceptScore W1991566352C71924100 @default.
- W1991566352 hasConceptScore W1991566352C86803240 @default.
- W1991566352 hasConceptScore W1991566352C8891405 @default.
- W1991566352 hasIssue "3" @default.
- W1991566352 hasLocation W19915663521 @default.
- W1991566352 hasLocation W19915663522 @default.
- W1991566352 hasOpenAccess W1991566352 @default.
- W1991566352 hasPrimaryLocation W19915663521 @default.
- W1991566352 hasRelatedWork W1252554981 @default.
- W1991566352 hasRelatedWork W1964765195 @default.
- W1991566352 hasRelatedWork W1969797792 @default.
- W1991566352 hasRelatedWork W2040369045 @default.
- W1991566352 hasRelatedWork W2090628788 @default.
- W1991566352 hasRelatedWork W2091270288 @default.
- W1991566352 hasRelatedWork W2147040603 @default.
- W1991566352 hasRelatedWork W2329394409 @default.
- W1991566352 hasRelatedWork W2418431370 @default.
- W1991566352 hasRelatedWork W3203138030 @default.
- W1991566352 hasVolume "69" @default.
- W1991566352 isParatext "false" @default.
- W1991566352 isRetracted "false" @default.
- W1991566352 magId "1991566352" @default.
- W1991566352 workType "article" @default.