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- W1991570595 abstract "Day 3-4 PHA stimulated lymphocytes were found to respond against HLA-D without any period of latency, thus allowing a discriminative MLR reading as early as 24-48 h. The test is therefore characterized by the minute number of responding cells necessary (5 X 10(3)), a one-way reaction without additional treatment of the stimualtion normal lymphocytes (5 x 10(4)), and the rapid obtaining of data. We found the preliminary data testing its concordance with classical HLA-D typing encouraging and worthy of being tested on a larger scale. Using mitogen stimulated recipient cells stored frozen, HLA-D matching with potential donors was found to be feasible within 24-48 h. The mechanism of such a prompt response by mitogen stimulated lymphocytes is unknown but appears to be independent of the nature and dose of a given mitogen." @default.
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- W1991570595 date "2008-12-11" @default.
- W1991570595 modified "2023-09-27" @default.
- W1991570595 title "A Rapid HLA-D Matching Method using PHA Blasts as Responding Cells (Preliminary Data on PHA Blasts HLA-D Typing)" @default.
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- W1991570595 doi "https://doi.org/10.1111/j.1399-0039.1976.tb00561.x" @default.
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