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- W1991595020 abstract "The corpus luteum of a number of species, including pig, contains quantities of cholesterol esters [ 1, 2, 31 which vary in concentration during the oestrus cycle [4] . Since an inverse relationship obtains between the amount of cholesterol esters present, and the progestational secretory activity [l] it was proposed that the sterol esters were stored precursors for ovarian steroidogenesis [4, 5, 61. That luteinizing hormone, which stimulates steroidogenesis, induces depletion of ovarian cholesterol esters [7, 81 is well established. The present study demonstrates that (i) cholesterol from cholesterol-fatty acids (FA) ester can be converted to pregnenolone and progesterone in luteal mitochondria and (ii) that the FA moiety of the sterol ester provides a potential source of electrons for the steroid hydroxylation reactions necessary for this conversion. The cholesterol side-chain cleavage (SCC) reaction is energy dependent when FA is the sole source of electrons." @default.
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- W1991595020 date "1971-09-15" @default.
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- W1991595020 title "Cholesterol esters and steroidogenesis in pig corpora lutea" @default.
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- W1991595020 doi "https://doi.org/10.1016/0014-5793(71)80562-8" @default.
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