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- W1991633332 abstract "The previously reported preparation of O-[11C]methyl-l-tyrosine ([11C]MT), a promising tumor imaging agent, has been now considerably simplified and automated. Main changes were the use of [11C]methyl iodide ([11C]MeI) in the reaction with l-tyrosine disodium and the use of solid phase extraction on commercially available cartridges instead of HPLC for the final purification. An injectable saline solution of [11C]MT was obtained within 30 min after EOB with radiochemical yield of ca. 60% (decay-corrected, based on [11C]MeI). Radiochemical purity was over 97%. The automated preparation was carried out using a miniature module employing manifold valves." @default.
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- W1991633332 date "2005-07-01" @default.
- W1991633332 modified "2023-09-26" @default.
- W1991633332 title "Simple automated preparation of O-[11C]methyl-l-tyrosine for routine clinical use" @default.
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- W1991633332 doi "https://doi.org/10.1016/j.apradiso.2005.01.014" @default.
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