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- W1991647551 abstract "The cable model of a passive, myelinated fiber is derived using the theory of electromagnetic propagation in periodic structures. The cable may be excited by an intracellular source or by an arbitrary, time-varying, applied extracellular field. When the cable is stimulated by a distant source, its properties are qualitatively similar to an unmyelinated fiber. Under these conditions relative threshold is proportional to the cube of the source distance and inversely proportional to the square of the fiber diameter. Electrical parameters of the model are chosen where possible, from mammalian peripheral nerve and anatomic parameters from cat auditory nerve. Several anatomic representations of the paranodal region are analyzed for their effects on the length and time constants of the fibers. Sensitivity of the model to parameter changes is studied. The linear model reliably predicts the effects of fiber size and electrode-fiber separation on threshold of cat dorsal column fibers to extracellular electrical stimulation." @default.
- W1991647551 created "2016-06-24" @default.
- W1991647551 creator A5011643678 @default.
- W1991647551 date "1988-12-01" @default.
- W1991647551 modified "2023-10-16" @default.
- W1991647551 title "Analytical theory for extracellular electrical stimulation of nerve with focal electrodes. I. Passive unmyelinated axon" @default.
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- W1991647551 doi "https://doi.org/10.1016/s0006-3495(88)83035-2" @default.
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