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- W1991654554 abstract "To the Editor.— The Preliminary Communication by Nimer et al 1 on the cholesterol-lowering activity of granulocyte-macrophage colony-stimulating factor that appeared in the December 9 issue ofThe Journalwas interesting, but indeed preliminary. There is a piece of important information that was omitted from this study: the total cholesterol and triglyceride levels were measured, but there was no measurement of high-density lipoprotein cholesterol. The triglyceride levels were not changed significantly and thus it was assumed the levels of very low-density lipoprotein cholesterol did not change. How much of the cholesterol-lowering effect of granulocyte-macrophage colony-stimulating factor was from lowering of low-density lipoprotein cholesterol and how much from lowering of high-density lipoprotein cholesterol was not determined. If there was a significant reduction in high-density lipoprotein cholesterol in addition to the reduction in low-density lipoprotein cholesterol, any potential benefit in the prevention of atherosclerosis would be negated—especially if there was an unfavorable" @default.
- W1991654554 created "2016-06-24" @default.
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- W1991654554 date "1989-04-28" @default.
- W1991654554 modified "2023-10-18" @default.
- W1991654554 title "Lowering Cholesterol With Granulocyte-Macrophage Colony-Stimulating Factor" @default.
- W1991654554 cites W1986714515 @default.
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- W1991654554 doi "https://doi.org/10.1001/jama.1989.03420160055024" @default.
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