FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1991656925> ?p ?o ?g. }

• W1991656925 endingPage "140" @default.
• W1991656925 startingPage "130" @default.
• W1991656925 abstract "ObjectiveTo explore associations between exposure to metals and male reproductive hormone levels.DesignCross-sectional epidemiology study with adjustment for potential confounders.SettingUniversity Medical Center.Patient(s)Men recruited through two infertility clinics in Michigan.Intervention(s)Metal concentrations and reproductive hormone levels were measured in blood samples collected from 219 men.Main Outcome Measure(s)Serum FSH, LH, inhibin B, T, and sex hormone-binding globulin levels.Result(s)Cadmium, copper, and lead were all significantly or suggestively positively associated with T when modeled individually, findings that are consistent with limited previous human and animal studies. Conversely, molybdenum was associated with reduced T. A significant inverse trend between molybdenum and T remained when additionally considering other metals in the model, and a positive association between T and zinc was also found. Finally, in exploratory analysis there was evidence for an interaction between molybdenum and zinc, whereby high molybdenum was associated with a 37% reduction in T (relative to the population median level) among men with low zinc.Conclusion(s)Although reductions in T and reproductive toxicity after molybdenum exposure have been previously demonstrated in animal studies, more research is needed to determine whether molybdenum poses a risk to human reproductive health. To explore associations between exposure to metals and male reproductive hormone levels. Cross-sectional epidemiology study with adjustment for potential confounders. University Medical Center. Men recruited through two infertility clinics in Michigan. Metal concentrations and reproductive hormone levels were measured in blood samples collected from 219 men. Serum FSH, LH, inhibin B, T, and sex hormone-binding globulin levels. Cadmium, copper, and lead were all significantly or suggestively positively associated with T when modeled individually, findings that are consistent with limited previous human and animal studies. Conversely, molybdenum was associated with reduced T. A significant inverse trend between molybdenum and T remained when additionally considering other metals in the model, and a positive association between T and zinc was also found. Finally, in exploratory analysis there was evidence for an interaction between molybdenum and zinc, whereby high molybdenum was associated with a 37% reduction in T (relative to the population median level) among men with low zinc. Although reductions in T and reproductive toxicity after molybdenum exposure have been previously demonstrated in animal studies, more research is needed to determine whether molybdenum poses a risk to human reproductive health." @default.
• W1991656925 created "2016-06-24" @default.
• W1991656925 creator A5009719215 @default.
• W1991656925 creator A5015175512 @default.
• W1991656925 creator A5022617720 @default.
• W1991656925 creator A5026864847 @default.
• W1991656925 creator A5039853092 @default.
• W1991656925 creator A5071464293 @default.
• W1991656925 creator A5073384036 @default.
• W1991656925 creator A5075354006 @default.
• W1991656925 creator A5075612284 @default.
• W1991656925 date "2010-01-01" @default.
• W1991656925 modified "2023-10-18" @default.
• W1991656925 title "Environmental exposure to metals and male reproductive hormones: circulating testosterone is inversely associated with blood molybdenum" @default.
• W1991656925 cites W1519969510 @default.
• W1991656925 cites W1549917918 @default.
• W1991656925 cites W1581385141 @default.
• W1991656925 cites W1958574545 @default.
• W1991656925 cites W1970646571 @default.
• W1991656925 cites W1982351125 @default.
• W1991656925 cites W1984017352 @default.
• W1991656925 cites W1984888506 @default.
• W1991656925 cites W1987384512 @default.
• W1991656925 cites W1987854264 @default.
• W1991656925 cites W1990247412 @default.
• W1991656925 cites W2009628191 @default.
• W1991656925 cites W2018182419 @default.
• W1991656925 cites W2019379404 @default.
• W1991656925 cites W2021135704 @default.
• W1991656925 cites W2025447551 @default.
• W1991656925 cites W2026118704 @default.
• W1991656925 cites W2033129336 @default.
• W1991656925 cites W2034427531 @default.
• W1991656925 cites W2036036101 @default.
• W1991656925 cites W2042521198 @default.
• W1991656925 cites W2043300062 @default.
• W1991656925 cites W2047226675 @default.
• W1991656925 cites W2049979612 @default.
• W1991656925 cites W2052257773 @default.
• W1991656925 cites W2053431267 @default.
• W1991656925 cites W2057542358 @default.
• W1991656925 cites W2058363509 @default.
• W1991656925 cites W2065746198 @default.
• W1991656925 cites W2066485162 @default.
• W1991656925 cites W2070831042 @default.
• W1991656925 cites W2070937649 @default.
• W1991656925 cites W2072623246 @default.
• W1991656925 cites W2079521417 @default.
• W1991656925 cites W2079536279 @default.
• W1991656925 cites W2083679958 @default.
• W1991656925 cites W2088579078 @default.
• W1991656925 cites W2092250343 @default.
• W1991656925 cites W2110941535 @default.
• W1991656925 cites W2137283822 @default.
• W1991656925 cites W2143788041 @default.
• W1991656925 cites W2145772643 @default.
• W1991656925 cites W2146252822 @default.
• W1991656925 cites W2150526953 @default.
• W1991656925 cites W2156702101 @default.
• W1991656925 cites W2159657989 @default.
• W1991656925 cites W2159832173 @default.
• W1991656925 cites W2162283563 @default.
• W1991656925 cites W2165126687 @default.
• W1991656925 cites W2165796764 @default.
• W1991656925 cites W2179567193 @default.
• W1991656925 cites W2398355717 @default.
• W1991656925 cites W38026353 @default.
• W1991656925 cites W4238274899 @default.
• W1991656925 cites W4255063111 @default.
• W1991656925 cites W47321816 @default.
• W1991656925 cites W2118581984 @default.
• W1991656925 doi "https://doi.org/10.1016/j.fertnstert.2008.09.044" @default.
• W1991656925 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2823119" @default.
• W1991656925 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18990371" @default.
• W1991656925 hasPublicationYear "2010" @default.
• W1991656925 type Work @default.
• W1991656925 sameAs 1991656925 @default.
• W1991656925 citedByCount "114" @default.
• W1991656925 countsByYear W19916569252012 @default.
• W1991656925 countsByYear W19916569252013 @default.
• W1991656925 countsByYear W19916569252014 @default.
• W1991656925 countsByYear W19916569252015 @default.
• W1991656925 countsByYear W19916569252016 @default.
• W1991656925 countsByYear W19916569252017 @default.
• W1991656925 countsByYear W19916569252018 @default.
• W1991656925 countsByYear W19916569252019 @default.
• W1991656925 countsByYear W19916569252020 @default.
• W1991656925 countsByYear W19916569252021 @default.
• W1991656925 countsByYear W19916569252022 @default.
• W1991656925 countsByYear W19916569252023 @default.
• W1991656925 crossrefType "journal-article" @default.
• W1991656925 hasAuthorship W1991656925A5009719215 @default.
• W1991656925 hasAuthorship W1991656925A5015175512 @default.
• W1991656925 hasAuthorship W1991656925A5022617720 @default.
• W1991656925 hasAuthorship W1991656925A5026864847 @default.
• W1991656925 hasAuthorship W1991656925A5039853092 @default.
• W1991656925 hasAuthorship W1991656925A5071464293 @default.
• W1991656925 hasAuthorship W1991656925A5073384036 @default.

• next