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- W1991657760 abstract "Several new 3-arylsulfonylmethyl-1,2,4-oxadiazole-5-carboxylic acid derivatives have been synthesized. A typical example, 3-[(4-chlorophenylsulfonyl)methyl]-1,2,4-oxadiazole-5-carboxylic acid ethyl ester (2c), was prepared from the reaction of 2-(4-chlorophenylsulfonyl)acetamide oxime (1c) with ethyl oxalyl chloride. The hydrazide derivative (3f) showed antihypertensive activity in rats. Various structural modifications to improve activity are discussed." @default.
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- W1991657760 date "1979-09-01" @default.
- W1991657760 modified "2023-09-26" @default.
- W1991657760 title "Synthesis of 3-arylsulfonylmethyl-1,2,4-oxadiazole-5-carboxylic acid derivatives" @default.
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- W1991657760 doi "https://doi.org/10.1002/jhet.5570160621" @default.
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