Matches in SemOpenAlex for { <https://semopenalex.org/work/W1991691567> ?p ?o ?g. }
Showing items 1 to 82 of
82
with 100 items per page.
- W1991691567 abstract "A large number of biological information has been available from genome sequencing and bioinformatics. To further understand the qualities of the biological networks (such as metabolic network) in the complex biological system, representations of integrated function <i>in silico</i> have been widely investigated, and various modeling approaches have been designed, most of which are based on detailed kinetic information except flux balance analysis (FBA). FBA, just based on stoichimetrical information of reactions, is a suitable method for the study of metabolic pathways, and it analyzes the behaviors of the network from the viewpoint of the whole system. Herein, this modeling approach has been utilized to reconstruct the mitochondrial metabolic network to integrate and analyze its capability of producing energy. Besides, extreme pathways analysis (EPA) and shadow prices analysis have also been integrated to study the interior characters of the network. Our modeling results have indicated for the first time that the covalent regulative property of pyruvate dehydrogenase is restrained by the feedback of acetyl-CoA. Combined with the biological experiments, these simulations <i>in silico</i> could be pretty useful for the further understanding of functions and characters of the biological network as a complex system." @default.
- W1991691567 created "2016-06-24" @default.
- W1991691567 creator A5009235827 @default.
- W1991691567 creator A5014035396 @default.
- W1991691567 creator A5019724726 @default.
- W1991691567 creator A5046017564 @default.
- W1991691567 creator A5058630792 @default.
- W1991691567 creator A5079570262 @default.
- W1991691567 date "2005-03-29" @default.
- W1991691567 modified "2023-09-23" @default.
- W1991691567 title "Flux balance analysis of myocardial mitochondrial metabolic network" @default.
- W1991691567 doi "https://doi.org/10.1117/12.589567" @default.
- W1991691567 hasPublicationYear "2005" @default.
- W1991691567 type Work @default.
- W1991691567 sameAs 1991691567 @default.
- W1991691567 citedByCount "0" @default.
- W1991691567 crossrefType "proceedings-article" @default.
- W1991691567 hasAuthorship W1991691567A5009235827 @default.
- W1991691567 hasAuthorship W1991691567A5014035396 @default.
- W1991691567 hasAuthorship W1991691567A5019724726 @default.
- W1991691567 hasAuthorship W1991691567A5046017564 @default.
- W1991691567 hasAuthorship W1991691567A5058630792 @default.
- W1991691567 hasAuthorship W1991691567A5079570262 @default.
- W1991691567 hasConcept C101810790 @default.
- W1991691567 hasConcept C104317684 @default.
- W1991691567 hasConcept C121332964 @default.
- W1991691567 hasConcept C14036430 @default.
- W1991691567 hasConcept C152662350 @default.
- W1991691567 hasConcept C160941953 @default.
- W1991691567 hasConcept C167091322 @default.
- W1991691567 hasConcept C178790620 @default.
- W1991691567 hasConcept C185592680 @default.
- W1991691567 hasConcept C186060115 @default.
- W1991691567 hasConcept C2775905019 @default.
- W1991691567 hasConcept C28225019 @default.
- W1991691567 hasConcept C32946077 @default.
- W1991691567 hasConcept C41008148 @default.
- W1991691567 hasConcept C54355233 @default.
- W1991691567 hasConcept C55493867 @default.
- W1991691567 hasConcept C62231903 @default.
- W1991691567 hasConcept C62520636 @default.
- W1991691567 hasConcept C68709404 @default.
- W1991691567 hasConcept C70721500 @default.
- W1991691567 hasConcept C86803240 @default.
- W1991691567 hasConceptScore W1991691567C101810790 @default.
- W1991691567 hasConceptScore W1991691567C104317684 @default.
- W1991691567 hasConceptScore W1991691567C121332964 @default.
- W1991691567 hasConceptScore W1991691567C14036430 @default.
- W1991691567 hasConceptScore W1991691567C152662350 @default.
- W1991691567 hasConceptScore W1991691567C160941953 @default.
- W1991691567 hasConceptScore W1991691567C167091322 @default.
- W1991691567 hasConceptScore W1991691567C178790620 @default.
- W1991691567 hasConceptScore W1991691567C185592680 @default.
- W1991691567 hasConceptScore W1991691567C186060115 @default.
- W1991691567 hasConceptScore W1991691567C2775905019 @default.
- W1991691567 hasConceptScore W1991691567C28225019 @default.
- W1991691567 hasConceptScore W1991691567C32946077 @default.
- W1991691567 hasConceptScore W1991691567C41008148 @default.
- W1991691567 hasConceptScore W1991691567C54355233 @default.
- W1991691567 hasConceptScore W1991691567C55493867 @default.
- W1991691567 hasConceptScore W1991691567C62231903 @default.
- W1991691567 hasConceptScore W1991691567C62520636 @default.
- W1991691567 hasConceptScore W1991691567C68709404 @default.
- W1991691567 hasConceptScore W1991691567C70721500 @default.
- W1991691567 hasConceptScore W1991691567C86803240 @default.
- W1991691567 hasLocation W19916915671 @default.
- W1991691567 hasOpenAccess W1991691567 @default.
- W1991691567 hasPrimaryLocation W19916915671 @default.
- W1991691567 hasRelatedWork W1865302071 @default.
- W1991691567 hasRelatedWork W1983785665 @default.
- W1991691567 hasRelatedWork W1984242440 @default.
- W1991691567 hasRelatedWork W1991691567 @default.
- W1991691567 hasRelatedWork W2072067873 @default.
- W1991691567 hasRelatedWork W2133150343 @default.
- W1991691567 hasRelatedWork W2416161358 @default.
- W1991691567 hasRelatedWork W2767502664 @default.
- W1991691567 hasRelatedWork W2950547188 @default.
- W1991691567 hasRelatedWork W3084362230 @default.
- W1991691567 isParatext "false" @default.
- W1991691567 isRetracted "false" @default.
- W1991691567 magId "1991691567" @default.
- W1991691567 workType "article" @default.