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- W1991733402 abstract "Despite appropriate medical therapy including diuretics, some patients get only a little benefits. We report our experience of marked improvement with tolvaptan in a patient with medically refractory severe heart failure. A-79-year old woman was diagnosed as dilated cardiomyopathy. Because of inobservance of water intake and medication, she had repeated hospitalization due to heart failure. Although she had orally taken furosemide 80 mg/day and, torasemide 16 mg/day, pimobendan 5.0 mg/day, carvedilol 2.5 mg/day after admission, she gained 3 kg weight and symptoms(short of breath, palpitation, edema) were worsened. In spite of addition of intravenous carperitide, body weight and symptoms didn’t improved. Then we started the oral administration of tolvaptan 15mg on the 11 hospital day. After administration of tolvaptan, we could lead to increase her urine output and improved lung congestion, edame of whole body. She didn’t need carperitide on 14 hospital day and discharged on 45 hospital day. After discharge, she continues tolvaptan 7.5mg/day and doesn’t readmission. Tolvaptan make it possible to discontinue of intravenous drug and discharge, furthermore avoid rehospitalization. We also report several similar experiences of tolvaptan use to the patients with medically refractory severe heart failure." @default.
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- W1991733402 date "2013-10-01" @default.
- W1991733402 modified "2023-09-24" @default.
- W1991733402 title "Successful Management with Tolvaptan in a Case with Medically Refractory Severe Heart Failure" @default.
- W1991733402 doi "https://doi.org/10.1016/j.cardfail.2013.08.438" @default.
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