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- W1991903521 abstract "This paper reviews the literature regarding the use of acoustic droplet vaporization (ADV) in clinical applications of imaging, embolic therapy, and therapeutic delivery. ADV is a physical process in which the pressure waves of ultrasound induce a phase transition that causes superheated liquid nanodroplets to form gas bubbles. The bubbles provide ultrasonic imaging contrast and other functions. ADV of perfluoropentane was used extensively in imaging for preclinical trials in the 1990s, but its use declined rapidly with the advent of other imaging agents. In the last decade, ADV was proposed and explored for embolic occlusion therapy, drug delivery, aberration correction, and high intensity focused ultrasound (HIFU) sensitization. Vessel occlusion via ADV has been explored in rodents and dogs and may be approaching clinical use. ADV for drug delivery is still in preclinical stages with initial applications to treat tumors in mice. Other techniques are still in preclinical studies but have potential for clinical use in specialty applications. Overall, ADV has a bright future in clinical application because the small size of nanodroplets greatly reduces the rate of clearance compared to larger contrast agent bubbles and yet provides the advantages of ultrasonographic contrast, acoustic cavitation, and nontoxicity of conventional perfluorocarbon contrast agent bubbles." @default.
- W1991903521 created "2016-06-24" @default.
- W1991903521 creator A5068925029 @default.
- W1991903521 creator A5084026877 @default.
- W1991903521 date "2013-01-01" @default.
- W1991903521 modified "2023-10-04" @default.
- W1991903521 title "Acoustic Droplet Vaporization in Biology and Medicine" @default.
- W1991903521 cites W104373058 @default.
- W1991903521 cites W1510888621 @default.
- W1991903521 cites W1965063429 @default.
- W1991903521 cites W1970935015 @default.
- W1991903521 cites W1976281106 @default.
- W1991903521 cites W1976638106 @default.
- W1991903521 cites W1977086661 @default.
- W1991903521 cites W1977093559 @default.
- W1991903521 cites W1978054090 @default.
- W1991903521 cites W1981942016 @default.
- W1991903521 cites W1982387849 @default.
- W1991903521 cites W1985858988 @default.
- W1991903521 cites W1993872066 @default.
- W1991903521 cites W1994832345 @default.
- W1991903521 cites W1995475798 @default.
- W1991903521 cites W1998579781 @default.
- W1991903521 cites W1998858103 @default.
- W1991903521 cites W1999827316 @default.
- W1991903521 cites W2000330791 @default.
- W1991903521 cites W2000381443 @default.
- W1991903521 cites W2001705635 @default.
- W1991903521 cites W2002838713 @default.
- W1991903521 cites W2004539235 @default.
- W1991903521 cites W2006373735 @default.
- W1991903521 cites W2006982433 @default.
- W1991903521 cites W2010832955 @default.
- W1991903521 cites W2017532125 @default.
- W1991903521 cites W2017568670 @default.
- W1991903521 cites W2019138771 @default.
- W1991903521 cites W2019222187 @default.
- W1991903521 cites W2023085863 @default.
- W1991903521 cites W2026489104 @default.
- W1991903521 cites W2026761805 @default.
- W1991903521 cites W2032526594 @default.
- W1991903521 cites W2034411464 @default.
- W1991903521 cites W2037236698 @default.
- W1991903521 cites W2037253046 @default.
- W1991903521 cites W2039759027 @default.
- W1991903521 cites W2042574165 @default.
- W1991903521 cites W2048690698 @default.
- W1991903521 cites W2053684203 @default.
- W1991903521 cites W2056410958 @default.
- W1991903521 cites W2058379099 @default.
- W1991903521 cites W2061501935 @default.
- W1991903521 cites W2062677709 @default.
- W1991903521 cites W2063400793 @default.
- W1991903521 cites W2063729179 @default.
- W1991903521 cites W2065166533 @default.
- W1991903521 cites W2070003597 @default.
- W1991903521 cites W2071612402 @default.
- W1991903521 cites W2074029441 @default.
- W1991903521 cites W2075871812 @default.
- W1991903521 cites W2077030769 @default.
- W1991903521 cites W2078058143 @default.
- W1991903521 cites W2083374899 @default.
- W1991903521 cites W2088659772 @default.
- W1991903521 cites W2089119446 @default.
- W1991903521 cites W2094097178 @default.
- W1991903521 cites W2095662328 @default.
- W1991903521 cites W2096970792 @default.
- W1991903521 cites W2098946064 @default.
- W1991903521 cites W2106709451 @default.
- W1991903521 cites W2108623236 @default.
- W1991903521 cites W2118713390 @default.
- W1991903521 cites W2130592920 @default.
- W1991903521 cites W2132621668 @default.
- W1991903521 cites W2142791646 @default.
- W1991903521 cites W2154250540 @default.
- W1991903521 cites W2156766018 @default.
- W1991903521 cites W2164635920 @default.
- W1991903521 cites W2165837047 @default.
- W1991903521 cites W2167623882 @default.
- W1991903521 cites W2169624838 @default.
- W1991903521 cites W2172103519 @default.
- W1991903521 cites W2339797268 @default.
- W1991903521 cites W2342316313 @default.
- W1991903521 cites W39616838 @default.
- W1991903521 cites W4255185157 @default.
- W1991903521 doi "https://doi.org/10.1155/2013/404361" @default.
- W1991903521 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3853706" @default.
- W1991903521 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24350267" @default.
- W1991903521 hasPublicationYear "2013" @default.
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