FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1991920897> ?p ?o ?g. }

• W1991920897 endingPage "919" @default.
• W1991920897 startingPage "911" @default.
• W1991920897 abstract "The importance of genetic predisposition, inflammation, and autoimmune mechanisms in the development of pulmonary arterial hypertension (PAH) is becoming increasingly clear. We hypothesized that the analysis of gene expression profiles from peripheral blood mononuclear cells would distinguish patients with PAH from normal volunteers. We also hypothesized that a subset of genes would discriminate between patients with idiopathic PAH and pulmonary hypertension related to secondary causes. Mononuclear cells were isolated from 15 patients diagnosed with PAH and 6 normal control subjects. Microarray expression was performed, and the expression profiles were analyzed for consistent and predictive differences in gene expression. We identified a signature set of 106 genes that discriminated with high certainty (p ⩽ 0.002) between patients with PAH and normal individuals. The results of the microarray analysis were retrospectively and prospectively confirmed by quantitative polymerase chain reaction for 2 of the 106 genes. Supervised clustering analysis generated a list of differentially expressed genes between patients with idiopathic and secondary causes of pulmonary hypertension. Microarray expression profiling of peripheral blood cells can discriminate between patients with PAH and normal volunteers. These findings may have important implications toward diagnosis, screening, and pathogenesis of this disease." @default.
• W1991920897 created "2016-06-24" @default.
• W1991920897 creator A5010401935 @default.
• W1991920897 creator A5022664012 @default.
• W1991920897 creator A5029671185 @default.
• W1991920897 creator A5062547544 @default.
• W1991920897 creator A5071945908 @default.
• W1991920897 creator A5074747228 @default.
• W1991920897 creator A5081200050 @default.
• W1991920897 creator A5084022307 @default.
• W1991920897 date "2004-10-15" @default.
• W1991920897 modified "2023-10-15" @default.
• W1991920897 title "Gene Microarray Analysis of Peripheral Blood Cells in Pulmonary Arterial Hypertension" @default.
• W1991920897 cites W1532393868 @default.
• W1991920897 cites W1651215666 @default.
• W1991920897 cites W1727290854 @default.
• W1991920897 cites W1834852860 @default.
• W1991920897 cites W1888035750 @default.
• W1991920897 cites W1967053372 @default.
• W1991920897 cites W1967246550 @default.
• W1991920897 cites W1976694529 @default.
• W1991920897 cites W1978347107 @default.
• W1991920897 cites W1981513838 @default.
• W1991920897 cites W1983418049 @default.
• W1991920897 cites W1986970734 @default.
• W1991920897 cites W1989174616 @default.
• W1991920897 cites W1991509879 @default.
• W1991920897 cites W1992526453 @default.
• W1991920897 cites W1996915488 @default.
• W1991920897 cites W2005232577 @default.
• W1991920897 cites W2016991226 @default.
• W1991920897 cites W2026469629 @default.
• W1991920897 cites W2027600997 @default.
• W1991920897 cites W2032402428 @default.
• W1991920897 cites W2043235003 @default.
• W1991920897 cites W2052325527 @default.
• W1991920897 cites W2055218751 @default.
• W1991920897 cites W2069041877 @default.
• W1991920897 cites W2078404836 @default.
• W1991920897 cites W2084892030 @default.
• W1991920897 cites W2088821548 @default.
• W1991920897 cites W2090348783 @default.
• W1991920897 cites W2092266379 @default.
• W1991920897 cites W2096393477 @default.
• W1991920897 cites W2096918975 @default.
• W1991920897 cites W2097413644 @default.
• W1991920897 cites W2098036595 @default.
• W1991920897 cites W2099659190 @default.
• W1991920897 cites W2107734982 @default.
• W1991920897 cites W2109363337 @default.
• W1991920897 cites W2110502951 @default.
• W1991920897 cites W2112604150 @default.
• W1991920897 cites W2128985829 @default.
• W1991920897 cites W2131989143 @default.
• W1991920897 cites W2133130553 @default.
• W1991920897 cites W2137062915 @default.
• W1991920897 cites W2137290980 @default.
• W1991920897 cites W2139530946 @default.
• W1991920897 cites W2141987653 @default.
• W1991920897 cites W2147246240 @default.
• W1991920897 cites W2155013589 @default.
• W1991920897 cites W2215499457 @default.
• W1991920897 cites W4239115538 @default.
• W1991920897 doi "https://doi.org/10.1164/rccm.200312-1686oc" @default.
• W1991920897 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15215156" @default.
• W1991920897 hasPublicationYear "2004" @default.
• W1991920897 type Work @default.
• W1991920897 sameAs 1991920897 @default.
• W1991920897 citedByCount "153" @default.
• W1991920897 countsByYear W19919208972012 @default.
• W1991920897 countsByYear W19919208972013 @default.
• W1991920897 countsByYear W19919208972014 @default.
• W1991920897 countsByYear W19919208972015 @default.
• W1991920897 countsByYear W19919208972016 @default.
• W1991920897 countsByYear W19919208972017 @default.
• W1991920897 countsByYear W19919208972018 @default.
• W1991920897 countsByYear W19919208972019 @default.
• W1991920897 countsByYear W19919208972020 @default.
• W1991920897 countsByYear W19919208972021 @default.
• W1991920897 countsByYear W19919208972022 @default.
• W1991920897 crossrefType "journal-article" @default.
• W1991920897 hasAuthorship W1991920897A5010401935 @default.
• W1991920897 hasAuthorship W1991920897A5022664012 @default.
• W1991920897 hasAuthorship W1991920897A5029671185 @default.
• W1991920897 hasAuthorship W1991920897A5062547544 @default.
• W1991920897 hasAuthorship W1991920897A5071945908 @default.
• W1991920897 hasAuthorship W1991920897A5074747228 @default.
• W1991920897 hasAuthorship W1991920897A5081200050 @default.
• W1991920897 hasAuthorship W1991920897A5084022307 @default.
• W1991920897 hasConcept C104317684 @default.
• W1991920897 hasConcept C126322002 @default.
• W1991920897 hasConcept C137061746 @default.
• W1991920897 hasConcept C142724271 @default.
• W1991920897 hasConcept C150194340 @default.
• W1991920897 hasConcept C18431079 @default.
• W1991920897 hasConcept C186836561 @default.
• W1991920897 hasConcept C202751555 @default.
• W1991920897 hasConcept C203014093 @default.

• next