Matches in SemOpenAlex for { <https://semopenalex.org/work/W1992006012> ?p ?o ?g. }
- W1992006012 abstract "The mechanism by which compressive mechanical stress affects glycosaminoglycan synthesis in the articular disk was investigated with a modified organ culture technique. Forty-eight male Sprague-Dawley rats were divided into three experimental groups and one control group of 12 animals each, aged 7 and 9 weeks. The experimental groups followed different regimens of stress applied for 25%, 75%, or 100% of the time during the total test period of 24 hours. Articular disks were stressed with flexible bottomed dishes (Flex I dishes, Flexcell Corp., McKeesport, Pa.) using the Flexercell Strain Unit (Flexcell Corp., McKeesport, Pa.) and incubated with [3H]-glucosamine for 24 hours. Samples were then collected, digested with Pronase-E, and after precipitation with cetylpyridinium chloride (CPC) and ethanol, the different glycosaminoglycans (GAGs) were separated by using cellulose acetate electrophoresis. The significant GAG types with stress were chondroitin6sulfate (C6S), hyaluronic acid (HA), and dermatan sulfate (DS). There was no significant relationship in the experimental groups between age and regimen of stress applied in either age. Higher stress regimens showed significantly higher proportions of C6S when compared with the controls, whereas HA appeared to decrease slightly and DS was not affected. Since C6S is the major component of hyaline cartilage, the results of this study suggest that compressive forces in the articular disk may stimulate the development of more cartilagenous-like properties with respect to GAG content." @default.
- W1992006012 created "2016-06-24" @default.
- W1992006012 creator A5019881431 @default.
- W1992006012 creator A5033225029 @default.
- W1992006012 creator A5086899563 @default.
- W1992006012 date "1995-04-01" @default.
- W1992006012 modified "2023-09-26" @default.
- W1992006012 title "Glycosaminoglycan synthesis in the rat articular disk in response to mechanical stress" @default.
- W1992006012 cites W1537394833 @default.
- W1992006012 cites W1964079155 @default.
- W1992006012 cites W1968473165 @default.
- W1992006012 cites W1976447271 @default.
- W1992006012 cites W1987512190 @default.
- W1992006012 cites W1988887471 @default.
- W1992006012 cites W1990683243 @default.
- W1992006012 cites W1995927377 @default.
- W1992006012 cites W1998681543 @default.
- W1992006012 cites W2002947324 @default.
- W1992006012 cites W2004154182 @default.
- W1992006012 cites W2004492566 @default.
- W1992006012 cites W2007804795 @default.
- W1992006012 cites W2013582146 @default.
- W1992006012 cites W2021438075 @default.
- W1992006012 cites W2035682116 @default.
- W1992006012 cites W2038081532 @default.
- W1992006012 cites W2042045265 @default.
- W1992006012 cites W2043503863 @default.
- W1992006012 cites W2049832073 @default.
- W1992006012 cites W2052214853 @default.
- W1992006012 cites W2058954195 @default.
- W1992006012 cites W2060845431 @default.
- W1992006012 cites W2073614167 @default.
- W1992006012 cites W2075104918 @default.
- W1992006012 cites W2077537617 @default.
- W1992006012 cites W2082494120 @default.
- W1992006012 cites W2082497544 @default.
- W1992006012 cites W2103749562 @default.
- W1992006012 cites W2116535999 @default.
- W1992006012 cites W2123665233 @default.
- W1992006012 cites W2137231634 @default.
- W1992006012 cites W2143873872 @default.
- W1992006012 cites W2166752018 @default.
- W1992006012 cites W4300643482 @default.
- W1992006012 doi "https://doi.org/10.1016/s0889-5406(95)70093-5" @default.
- W1992006012 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7709905" @default.
- W1992006012 hasPublicationYear "1995" @default.
- W1992006012 type Work @default.
- W1992006012 sameAs 1992006012 @default.
- W1992006012 citedByCount "43" @default.
- W1992006012 countsByYear W19920060122012 @default.
- W1992006012 countsByYear W19920060122013 @default.
- W1992006012 countsByYear W19920060122014 @default.
- W1992006012 countsByYear W19920060122016 @default.
- W1992006012 countsByYear W19920060122017 @default.
- W1992006012 crossrefType "journal-article" @default.
- W1992006012 hasAuthorship W1992006012A5019881431 @default.
- W1992006012 hasAuthorship W1992006012A5033225029 @default.
- W1992006012 hasAuthorship W1992006012A5086899563 @default.
- W1992006012 hasConcept C105702510 @default.
- W1992006012 hasConcept C126322002 @default.
- W1992006012 hasConcept C141071460 @default.
- W1992006012 hasConcept C153074725 @default.
- W1992006012 hasConcept C181199279 @default.
- W1992006012 hasConcept C185592680 @default.
- W1992006012 hasConcept C2776708817 @default.
- W1992006012 hasConcept C2777529286 @default.
- W1992006012 hasConcept C2778066728 @default.
- W1992006012 hasConcept C2778125326 @default.
- W1992006012 hasConcept C2778206598 @default.
- W1992006012 hasConcept C2779553658 @default.
- W1992006012 hasConcept C2780340462 @default.
- W1992006012 hasConcept C55493867 @default.
- W1992006012 hasConcept C58226133 @default.
- W1992006012 hasConcept C71924100 @default.
- W1992006012 hasConceptScore W1992006012C105702510 @default.
- W1992006012 hasConceptScore W1992006012C126322002 @default.
- W1992006012 hasConceptScore W1992006012C141071460 @default.
- W1992006012 hasConceptScore W1992006012C153074725 @default.
- W1992006012 hasConceptScore W1992006012C181199279 @default.
- W1992006012 hasConceptScore W1992006012C185592680 @default.
- W1992006012 hasConceptScore W1992006012C2776708817 @default.
- W1992006012 hasConceptScore W1992006012C2777529286 @default.
- W1992006012 hasConceptScore W1992006012C2778066728 @default.
- W1992006012 hasConceptScore W1992006012C2778125326 @default.
- W1992006012 hasConceptScore W1992006012C2778206598 @default.
- W1992006012 hasConceptScore W1992006012C2779553658 @default.
- W1992006012 hasConceptScore W1992006012C2780340462 @default.
- W1992006012 hasConceptScore W1992006012C55493867 @default.
- W1992006012 hasConceptScore W1992006012C58226133 @default.
- W1992006012 hasConceptScore W1992006012C71924100 @default.
- W1992006012 hasLocation W19920060121 @default.
- W1992006012 hasLocation W19920060122 @default.
- W1992006012 hasOpenAccess W1992006012 @default.
- W1992006012 hasPrimaryLocation W19920060121 @default.
- W1992006012 hasRelatedWork W1817704205 @default.
- W1992006012 hasRelatedWork W1992006012 @default.
- W1992006012 hasRelatedWork W2013159469 @default.
- W1992006012 hasRelatedWork W2014033285 @default.
- W1992006012 hasRelatedWork W2020201209 @default.
- W1992006012 hasRelatedWork W2021792988 @default.