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• W1992006293 abstract "Pigs were vaccinated with the emergency inactivated foot-and-mouth disease virus (FMDV) vaccine—water-in-oil-in-water emulsion with Montanide ISA206—known to protect after 3–5 days. Peripheral blood leukocyte (PBL) sub-populations did not differ between vaccinates and controls post-vaccination. There was neither lymphopenia nor inflammatory reaction. FMDV-specific antibody and T lymphocyte activity developed in the vaccinates. Virus-induced Th1-like cytokine protein and mRNA (IFNγ and IL-2) were identified, particularly IFNγ. Th2-like cytokine protein and mRNA (IL-4 and IL-6) were also induced in an FMDV-specific manner. IL-10 was induced by both virus and mock antigen. The current emergency FMDV vaccine induces a diverse immune defence network—innate, and both Th1-like and Th2-like responses—without adverse reactions such as lymphopenia or inflammatory responses." @default.
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• W1992006293 date "2005-01-01" @default.
• W1992006293 modified "2023-09-26" @default.
• W1992006293 title "Immune response characteristics following emergency vaccination of pigs against foot-and-mouth disease" @default.
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• W1992006293 doi "https://doi.org/10.1016/j.vaccine.2004.07.034" @default.
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