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• W1992019929 endingPage "526" @default.
• W1992019929 startingPage "507" @default.
• W1992019929 abstract "Wegener's granulomatosis (WG) is characterized by granulomatous lesions and vasculitic disease manifestations. Granulomatous lesions are found in the upper and lower respiratory tract (eg, granulomatous sinusitis, orbital masses, and pulmonary granuloma), whereas vasculitic manifestations occur frequently in lung (alveolar hemorrhage) and kidney (glomerulonephritis). Vasculitis is typically associated with antineutrophil cytoplasmic antibodies (ANCA) directed against proteinase 3. WG has been traditionally associated with a poor outcome and increased mortality as documented by numerous studies; however, recent cohort studies report an improved outcome, probably a consequence of increased awareness leading to an earlier diagnosis, and to improved treatment strategies derived from evidence from controlled trials. Treatment regimens for WG, adapted to disease stage and activity, are reviewed and discussed in this article." @default.
• W1992019929 created "2016-06-24" @default.
• W1992019929 creator A5023283683 @default.
• W1992019929 creator A5031865300 @default.
• W1992019929 creator A5082668263 @default.
• W1992019929 date "2010-08-01" @default.
• W1992019929 modified "2023-09-27" @default.
• W1992019929 title "Clinical Manifestations and Treatment of Wegener's Granulomatosis" @default.
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