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- W1992021083 abstract "Polyclonal antibodies which recognize the ρ-subunits of the GABAC receptor were applied to sections of the rat retina. Strong punctate immunoreactivity was found in the inner plexiform layer (IPL), which was shown by electron microscopy to represent a clustering of the GABAC receptors at synaptic sites. During postnatal development diffuse ρ-immunoreactivity was first observed at postnatal day P3. Distinct labelling of bipolar cells appeared at P7 and punctate, synaptic labelling was observed at P10. In order to show that the ρ-immunoreactive puncta coincide with the axons of bipolar cells, double immunostainings of retinal sections with an antiserum against syntaxin 3 and with the ρ-antiserum were performed. The experiments showed that ρ-immunoreactive puncta are preferentially located on the axon terminals of rod and cone bipolar cells. In order to determine whether GABAC receptor ρ-subunits coassemble with GABAA receptor subunits, double-labelling experiments were performed with subunit specific antisera. Punctate, putative synaptic clustering was observed with all antisera applied, however, GABAC receptor expressing puncta did not coincide with GABAA receptor containing puncta. This suggests that there are no synaptic GABA receptors in the retina in which GABAA and GABAC receptor subunits are coassembled. Similar double-labelling experiments were also performed to find out whether GABAC receptors and glycine receptors are colocalized. They were clustered at different synapses. This suggests that synaptic GABAC receptors consist of ρ-subunits and are not coassembled with GABAA- or glycine-receptor subunits." @default.
- W1992021083 created "2016-06-24" @default.
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- W1992021083 creator A5065386092 @default.
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- W1992021083 date "1998-01-01" @default.
- W1992021083 modified "2023-10-17" @default.
- W1992021083 title "Synaptic clustering of GABA <sub>C</sub> receptor ρ‐subunits in the rat retina" @default.
- W1992021083 cites W1509427350 @default.
- W1992021083 cites W1523657314 @default.
- W1992021083 cites W1526360825 @default.
- W1992021083 cites W1538927534 @default.
- W1992021083 cites W1542694382 @default.
- W1992021083 cites W1562806058 @default.
- W1992021083 cites W1710559804 @default.
- W1992021083 cites W1740455381 @default.
- W1992021083 cites W1825905345 @default.
- W1992021083 cites W1872667629 @default.
- W1992021083 cites W1920511465 @default.
- W1992021083 cites W1947718130 @default.
- W1992021083 cites W1951170463 @default.
- W1992021083 cites W1970570515 @default.
- W1992021083 cites W1983111091 @default.
- W1992021083 cites W1984537495 @default.
- W1992021083 cites W1992065426 @default.
- W1992021083 cites W1992759024 @default.
- W1992021083 cites W1996033662 @default.
- W1992021083 cites W2003127982 @default.
- W1992021083 cites W2003152729 @default.
- W1992021083 cites W2008051797 @default.
- W1992021083 cites W2013253007 @default.
- W1992021083 cites W2014577411 @default.
- W1992021083 cites W2015562927 @default.
- W1992021083 cites W2025700116 @default.
- W1992021083 cites W2026559607 @default.
- W1992021083 cites W2027465915 @default.
- W1992021083 cites W2028674613 @default.
- W1992021083 cites W2032415987 @default.
- W1992021083 cites W2036453841 @default.
- W1992021083 cites W2043241080 @default.
- W1992021083 cites W2045300940 @default.
- W1992021083 cites W2052415893 @default.
- W1992021083 cites W2057378701 @default.
- W1992021083 cites W2057900845 @default.
- W1992021083 cites W2058575458 @default.
- W1992021083 cites W2059818802 @default.
- W1992021083 cites W2063996780 @default.
- W1992021083 cites W2066526224 @default.
- W1992021083 cites W2077516044 @default.
- W1992021083 cites W2077860191 @default.
- W1992021083 cites W2079158149 @default.
- W1992021083 cites W2080506185 @default.
- W1992021083 cites W2086481761 @default.
- W1992021083 cites W2087045924 @default.
- W1992021083 cites W2090196720 @default.
- W1992021083 cites W2090776289 @default.
- W1992021083 cites W2091376917 @default.
- W1992021083 cites W2095018051 @default.
- W1992021083 cites W2103791788 @default.
- W1992021083 cites W2114972922 @default.
- W1992021083 cites W2115029196 @default.
- W1992021083 cites W2119527481 @default.
- W1992021083 cites W2126259509 @default.
- W1992021083 cites W2127759683 @default.
- W1992021083 cites W2129899041 @default.
- W1992021083 cites W2131231986 @default.
- W1992021083 cites W2138427974 @default.
- W1992021083 cites W2139549247 @default.
- W1992021083 cites W2142273844 @default.
- W1992021083 cites W2144965832 @default.
- W1992021083 cites W2153283555 @default.
- W1992021083 cites W2160491003 @default.
- W1992021083 cites W2170688101 @default.
- W1992021083 cites W2259570855 @default.
- W1992021083 cites W2337967379 @default.
- W1992021083 cites W2341332902 @default.
- W1992021083 cites W4242690077 @default.
- W1992021083 cites W4248516430 @default.
- W1992021083 cites W4251535289 @default.
- W1992021083 cites W4256733296 @default.
- W1992021083 cites W82992345 @default.
- W1992021083 cites W92137870 @default.
- W1992021083 doi "https://doi.org/10.1046/j.1460-9568.1998.00005.x" @default.
- W1992021083 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9753119" @default.
- W1992021083 hasPublicationYear "1998" @default.
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