Matches in SemOpenAlex for { <https://semopenalex.org/work/W1992022037> ?p ?o ?g. }
- W1992022037 endingPage "1475" @default.
- W1992022037 startingPage "1463" @default.
- W1992022037 abstract "Caspi et al. (2003) found an interaction between the serotonin transporter polymorphism gene (5-HTTLPR) and stressful life events on depression. Subsequent attempts to replicate have been inconsistent. The present research included long allele variants modified by SNP rs25531 and tested the interaction on adolescents' trajectories of anxious/depressed symptoms, with consideration of possible age effects. Adolescents (N = 574), of whom 436 were genotyped, were followed from ages 12 to 17. Analyses demonstrated a G × E interaction in predicting the development of anxious/depressed symptoms. Specifically, adolescents with lower serotonin transcriptional efficiency (TE) genotypes whose mothers reported more stressful events were reported to show more anxious/depressed symptoms and greater increases in the development of symptoms of anxiety and depression than were higher TE adolescents, particularly at ages 16 and 17. Interactions did not differ by gender. Findings demonstrate that stress may affect adolescents' likelihood of experiencing anxious/depressed symptoms when they have a low serotonin TE (A/G-modified 5-HTTLPR) genotype and suggest that the vulnerability may be stronger in late than early adolescence." @default.
- W1992022037 created "2016-06-24" @default.
- W1992022037 creator A5021183446 @default.
- W1992022037 creator A5021811638 @default.
- W1992022037 creator A5035759872 @default.
- W1992022037 creator A5040263591 @default.
- W1992022037 creator A5040911518 @default.
- W1992022037 creator A5061967443 @default.
- W1992022037 creator A5070062193 @default.
- W1992022037 creator A5082142520 @default.
- W1992022037 date "2012-01-01" @default.
- W1992022037 modified "2023-10-10" @default.
- W1992022037 title "Interaction between serotonin transporter polymorphism (5-HTTLPR) and stressful life events in adolescents' trajectories of anxious/depressed symptoms." @default.
- W1992022037 cites W1556541022 @default.
- W1992022037 cites W1581378799 @default.
- W1992022037 cites W1792345659 @default.
- W1992022037 cites W1881287185 @default.
- W1992022037 cites W1961509528 @default.
- W1992022037 cites W1966300530 @default.
- W1992022037 cites W1969570897 @default.
- W1992022037 cites W1978580001 @default.
- W1992022037 cites W1979418246 @default.
- W1992022037 cites W1980207569 @default.
- W1992022037 cites W1984455353 @default.
- W1992022037 cites W1994286942 @default.
- W1992022037 cites W2001028204 @default.
- W1992022037 cites W2002432716 @default.
- W1992022037 cites W2002996606 @default.
- W1992022037 cites W2012367239 @default.
- W1992022037 cites W2018290008 @default.
- W1992022037 cites W2021622240 @default.
- W1992022037 cites W2027369775 @default.
- W1992022037 cites W2032442232 @default.
- W1992022037 cites W2034325147 @default.
- W1992022037 cites W2034534819 @default.
- W1992022037 cites W2042170262 @default.
- W1992022037 cites W2043336959 @default.
- W1992022037 cites W2044750305 @default.
- W1992022037 cites W2048013405 @default.
- W1992022037 cites W2050035705 @default.
- W1992022037 cites W2054205221 @default.
- W1992022037 cites W2055218553 @default.
- W1992022037 cites W2058397180 @default.
- W1992022037 cites W2062405004 @default.
- W1992022037 cites W2069799601 @default.
- W1992022037 cites W2071338647 @default.
- W1992022037 cites W2072976491 @default.
- W1992022037 cites W2074604892 @default.
- W1992022037 cites W2077674356 @default.
- W1992022037 cites W2088813524 @default.
- W1992022037 cites W2097430457 @default.
- W1992022037 cites W2100230238 @default.
- W1992022037 cites W2102844013 @default.
- W1992022037 cites W2103093164 @default.
- W1992022037 cites W2106095564 @default.
- W1992022037 cites W2109026965 @default.
- W1992022037 cites W2114792171 @default.
- W1992022037 cites W2119844886 @default.
- W1992022037 cites W2122246853 @default.
- W1992022037 cites W2123722790 @default.
- W1992022037 cites W2124485063 @default.
- W1992022037 cites W2127606855 @default.
- W1992022037 cites W2138962612 @default.
- W1992022037 cites W2145430042 @default.
- W1992022037 cites W2151135161 @default.
- W1992022037 cites W2159485259 @default.
- W1992022037 cites W2162196924 @default.
- W1992022037 cites W2170245235 @default.
- W1992022037 cites W2170846744 @default.
- W1992022037 cites W2171097731 @default.
- W1992022037 cites W2285822493 @default.
- W1992022037 cites W2489684274 @default.
- W1992022037 cites W2613456039 @default.
- W1992022037 cites W3025192047 @default.
- W1992022037 cites W3086315876 @default.
- W1992022037 cites W3144847119 @default.
- W1992022037 cites W3151816160 @default.
- W1992022037 cites W575739181 @default.
- W1992022037 cites W93044161 @default.
- W1992022037 cites W2053127039 @default.
- W1992022037 cites W2075661210 @default.
- W1992022037 doi "https://doi.org/10.1037/a0027471" @default.
- W1992022037 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3404160" @default.
- W1992022037 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22390669" @default.
- W1992022037 hasPublicationYear "2012" @default.
- W1992022037 type Work @default.
- W1992022037 sameAs 1992022037 @default.
- W1992022037 citedByCount "47" @default.
- W1992022037 countsByYear W19920220372012 @default.
- W1992022037 countsByYear W19920220372013 @default.
- W1992022037 countsByYear W19920220372014 @default.
- W1992022037 countsByYear W19920220372015 @default.
- W1992022037 countsByYear W19920220372016 @default.
- W1992022037 countsByYear W19920220372017 @default.
- W1992022037 countsByYear W19920220372018 @default.
- W1992022037 countsByYear W19920220372019 @default.
- W1992022037 countsByYear W19920220372021 @default.
- W1992022037 countsByYear W19920220372023 @default.