FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1992022373> ?p ?o ?g. }

• W1992022373 endingPage "25" @default.
• W1992022373 startingPage "21" @default.
• W1992022373 abstract "Cisplatin (CP) is a widely used antineoplastic drug that exhibits gastrointestinal toxicity. We have previously shown that administration of a single dose of CP results in a decrease in the activities of several brush border membrane (BBM) enzymes, induces oxidative stress and alters the activities of several antioxidant enzymes in the small intestine of rats. In the present study we have investigated the effect of treatment with the dietary antioxidant caffeic acid (CA) on CP induced biochemical changes in the intestine. Administration of a single intraperitoneal dose of CP alone (6 mg/kg body weight) led to a decrease in the activities of the BBM enzymes, increase in lipid peroxidation, decrease in sulfhydryl groups and changes in the activities of catalase, superoxide dismutase, glutathione peroxidase, glucose 6-phosphate dehydrogenase, glutathione reductase, glutathione S-transferase and thioredoxin reductase. Administration of two doses of CA (each of 250 mg/kg body weight), at 15 and 120 min after treatment with CP, significantly attenuated the CP-induced changes in all these parameters but the administration of CA alone had no effect. These results suggest that CA is an effective agent in reducing the effects of CP on the intestine and could prove to be useful in alleviating the gastrointestinal toxicity of this drug." @default.
• W1992022373 created "2016-06-24" @default.
• W1992022373 creator A5023338166 @default.
• W1992022373 creator A5068277893 @default.
• W1992022373 creator A5088621768 @default.
• W1992022373 date "2013-01-01" @default.
• W1992022373 modified "2023-10-16" @default.
• W1992022373 title "Oral administration of caffeic acid ameliorates the effect of cisplatin on brush border membrane enzymes and antioxidant system in rat intestine" @default.
• W1992022373 cites W1546592314 @default.
• W1992022373 cites W1581414347 @default.
• W1992022373 cites W1590457525 @default.
• W1992022373 cites W1741860215 @default.
• W1992022373 cites W1775749144 @default.
• W1992022373 cites W191793640 @default.
• W1992022373 cites W1942309057 @default.
• W1992022373 cites W1965788245 @default.
• W1992022373 cites W1966112269 @default.
• W1992022373 cites W1974338718 @default.
• W1992022373 cites W1974750930 @default.
• W1992022373 cites W1978454448 @default.
• W1992022373 cites W1981522515 @default.
• W1992022373 cites W1987338970 @default.
• W1992022373 cites W1988782583 @default.
• W1992022373 cites W1992210660 @default.
• W1992022373 cites W2003572460 @default.
• W1992022373 cites W2012726316 @default.
• W1992022373 cites W2023500337 @default.
• W1992022373 cites W2038876417 @default.
• W1992022373 cites W2041805173 @default.
• W1992022373 cites W2043974573 @default.
• W1992022373 cites W2046731503 @default.
• W1992022373 cites W2052571684 @default.
• W1992022373 cites W2057045685 @default.
• W1992022373 cites W2057262948 @default.
• W1992022373 cites W2060123651 @default.
• W1992022373 cites W2063576996 @default.
• W1992022373 cites W2071874725 @default.
• W1992022373 cites W2082798463 @default.
• W1992022373 cites W2088003515 @default.
• W1992022373 cites W2088866343 @default.
• W1992022373 cites W2095096262 @default.
• W1992022373 cites W2095228276 @default.
• W1992022373 cites W2132001873 @default.
• W1992022373 cites W2172985285 @default.
• W1992022373 cites W74095970 @default.
• W1992022373 cites W90400283 @default.
• W1992022373 doi "https://doi.org/10.1016/j.etp.2011.05.004" @default.
• W1992022373 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21640567" @default.
• W1992022373 hasPublicationYear "2013" @default.
• W1992022373 type Work @default.
• W1992022373 sameAs 1992022373 @default.
• W1992022373 citedByCount "31" @default.
• W1992022373 countsByYear W19920223732012 @default.
• W1992022373 countsByYear W19920223732013 @default.
• W1992022373 countsByYear W19920223732014 @default.
• W1992022373 countsByYear W19920223732015 @default.
• W1992022373 countsByYear W19920223732016 @default.
• W1992022373 countsByYear W19920223732017 @default.
• W1992022373 countsByYear W19920223732018 @default.
• W1992022373 countsByYear W19920223732019 @default.
• W1992022373 countsByYear W19920223732020 @default.
• W1992022373 countsByYear W19920223732021 @default.
• W1992022373 countsByYear W19920223732022 @default.
• W1992022373 countsByYear W19920223732023 @default.
• W1992022373 crossrefType "journal-article" @default.
• W1992022373 hasAuthorship W1992022373A5023338166 @default.
• W1992022373 hasAuthorship W1992022373A5068277893 @default.
• W1992022373 hasAuthorship W1992022373A5088621768 @default.
• W1992022373 hasConcept C130316041 @default.
• W1992022373 hasConcept C165069038 @default.
• W1992022373 hasConcept C181199279 @default.
• W1992022373 hasConcept C185592680 @default.
• W1992022373 hasConcept C2775838275 @default.
• W1992022373 hasConcept C2777882243 @default.
• W1992022373 hasConcept C2778004101 @default.
• W1992022373 hasConcept C2778760513 @default.
• W1992022373 hasConcept C2778979269 @default.
• W1992022373 hasConcept C2780829032 @default.
• W1992022373 hasConcept C41625074 @default.
• W1992022373 hasConcept C538909803 @default.
• W1992022373 hasConcept C5426402 @default.
• W1992022373 hasConcept C55493867 @default.
• W1992022373 hasConcept C86803240 @default.
• W1992022373 hasConcept C98274493 @default.
• W1992022373 hasConceptScore W1992022373C130316041 @default.
• W1992022373 hasConceptScore W1992022373C165069038 @default.
• W1992022373 hasConceptScore W1992022373C181199279 @default.
• W1992022373 hasConceptScore W1992022373C185592680 @default.
• W1992022373 hasConceptScore W1992022373C2775838275 @default.
• W1992022373 hasConceptScore W1992022373C2777882243 @default.
• W1992022373 hasConceptScore W1992022373C2778004101 @default.
• W1992022373 hasConceptScore W1992022373C2778760513 @default.
• W1992022373 hasConceptScore W1992022373C2778979269 @default.
• W1992022373 hasConceptScore W1992022373C2780829032 @default.
• W1992022373 hasConceptScore W1992022373C41625074 @default.
• W1992022373 hasConceptScore W1992022373C538909803 @default.
• W1992022373 hasConceptScore W1992022373C5426402 @default.
• W1992022373 hasConceptScore W1992022373C55493867 @default.

• next