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- W1992023392 abstract "The energy-linked uptake of Ca2+ by heart mitochondria is inhibited by Mg2+ and this has been exploited to devise an inhibitor-stop method which has permitted direct measurements of the kinetics of Ca2+ uptake. The initial rate of Ca2+ influx has also been measured directly using a Ca2+-selective electrode. Half-maximal rate of uptake is attained at 12–15 μM Ca2+ and the maximum velocity is about 1.4 nmol of Ca2+/mg of protein per s at 25°C. The rate versus Ca2+ -concentration curve is hyperbolic but becomes sigmoidal in the presence of Mg2+. Inorganic phosphate stimulates the initial rate of Ca2+ influx 2 to 4 times." @default.
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- W1992023392 date "1976-10-01" @default.
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- W1992023392 title "A Kinetic Study of the Energy-Linked Influx of Ca2+ into Heart Mitochondria" @default.
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- W1992023392 doi "https://doi.org/10.1111/j.1432-1033.1976.tb10927.x" @default.
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