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- W1992024180 abstract "The present study was undertaken to determine the efferent projections of the lateral dorsal nucleus of the rat thalamus using procedures based on anterograde degeneration as well as anterograde and retrograde axoplasmic transport. Discrete lesions or injections of [3H]leucine were placed at separate anterior and posterior loci in the lateral dorsal nucleus to determine if these portions of the nucleus project to different terminal fields. From both loci, labeled or degenerating axons coursed laterally from the nucleus, passed through the superior thalamic radiation, and entered the caudate-putamen complex. From there, a large number of fibers coursed rostrally in the album cerebri and terminated in layers I and III of anterior cingulate cortical areas 23 and 24. The remaining fibers passed dorsally and entered the posterior cingulate cortex where terminations were observed in areas 29b and 29c. Within area 29b, terminations were arranged parallel to the surface in layers I and III at its border with area 29c. In animals with anteriorly placed lesions or injections, area 29c exhibited input in layers I, III, and IV at the lip of the hemisphere. After injections in the posterior part of the lateral dorsal nucleus, a denser distribution was observed within the same layers at the border of areas 29b and 29c. Projections and areas of termination were also observed from both anterior and posterior lesions or injection sites to the laminae dissecans and externa of the pre- and parasubiculum. These projections were confirmed by retrograde axoplasmic transport of horseradish peroxidase after its injection in the cingulate and subicular cortices. These results indicate that the lateral dorsal nucleus, through its prominent connections with the anterior and posterior parts of the cingulate cortex and subicular region may have significant connections with the limbic system." @default.
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- W1992024180 date "1980-04-01" @default.
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- W1992024180 title "Efferent projections of the lateral dorsal nucleus in the rat" @default.
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- W1992024180 doi "https://doi.org/10.1016/0014-4886(80)90075-8" @default.
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