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- W1992031214 abstract "Androgen (AR) and estrogen (ERalpha and ERbeta) receptors are primary targets in the treatment of hormone-sensitive tumors such as prostate or breast cancers. Because of their diverse and important roles in normal and pathologic physiology, these nuclear receptors have prompted intense research. Here, we review how structural studies conducted over the past several years on AR and ERs have provided significant advances in our comprehension of androgen and estrogen signaling and how this information can be used in the fight against cancer." @default.
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- W1992031214 date "2007-07-01" @default.
- W1992031214 modified "2023-09-25" @default.
- W1992031214 title "Androgen and estrogen receptors: Potential of crystallography in the fight against cancer" @default.
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- W1992031214 doi "https://doi.org/10.1016/j.biocel.2007.01.001" @default.
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