Matches in SemOpenAlex for { <https://semopenalex.org/work/W1992059246> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W1992059246 endingPage "43" @default.
- W1992059246 startingPage "37" @default.
- W1992059246 abstract "The antiinflammatory activity of three hydrosoluble aryldimethyltriazenes has been examined on the carrageenin induced edema in guinea pig. The administration of equitoxic dosages of p-(3,3-dimethyl-1-triazeno)benzoic acid potassium salt (DM-COOK) and p-(3,3-dimethyl-1-triazeno)sulfonic acid sodium salt (DM-SO3Na) 1 h after carrageenin application, causes 4 h later a similar and statistically significant reduction of paw swelling by about 40% whereas, p-alanylphenyl-3,3-dimethyl-1-triazeno (DM-ALA(OH)) is inactive. Of the two active compounds, DM-COOK displays interesting properties, being rapidly active and causing a peak of inhibition higher than that caused by DM-SO3Na. The antiinflammatory activity of DM-COOK is comparable with that caused by 5 mg/kg indomethacin and 200 mg/kg phenylbutazone. However, DM-COOK, unlike indomethacin, causes an inhibition of leukocyte migration into the peritoneal cavity induced by casein treatment, thus indicating a different mechanism of action. This effect needs clarification and seems not to be correlated to cytotoxicity of the drug for migrating white blood cells, as evidenced by in vitro' examination." @default.
- W1992059246 created "2016-06-24" @default.
- W1992059246 creator A5006541709 @default.
- W1992059246 creator A5015457679 @default.
- W1992059246 creator A5027632014 @default.
- W1992059246 creator A5089465265 @default.
- W1992059246 date "1985-01-01" @default.
- W1992059246 modified "2023-09-23" @default.
- W1992059246 title "Antiinflammatory action of hydrosoluble dimethyl-triazenes on the carrageenin-induced edema in guinea pigs" @default.
- W1992059246 cites W1981318795 @default.
- W1992059246 cites W1985091767 @default.
- W1992059246 cites W1991951217 @default.
- W1992059246 cites W2003478252 @default.
- W1992059246 cites W2007532690 @default.
- W1992059246 cites W2009523965 @default.
- W1992059246 cites W2015889277 @default.
- W1992059246 cites W2050557338 @default.
- W1992059246 cites W2056825494 @default.
- W1992059246 cites W2060747329 @default.
- W1992059246 cites W2062899093 @default.
- W1992059246 cites W2159548820 @default.
- W1992059246 cites W2318740895 @default.
- W1992059246 doi "https://doi.org/10.1016/s0009-2797(85)80082-x" @default.
- W1992059246 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3995654" @default.
- W1992059246 hasPublicationYear "1985" @default.
- W1992059246 type Work @default.
- W1992059246 sameAs 1992059246 @default.
- W1992059246 citedByCount "14" @default.
- W1992059246 countsByYear W19920592462015 @default.
- W1992059246 countsByYear W19920592462016 @default.
- W1992059246 countsByYear W19920592462017 @default.
- W1992059246 countsByYear W19920592462018 @default.
- W1992059246 countsByYear W19920592462019 @default.
- W1992059246 countsByYear W19920592462020 @default.
- W1992059246 countsByYear W19920592462021 @default.
- W1992059246 crossrefType "journal-article" @default.
- W1992059246 hasAuthorship W1992059246A5006541709 @default.
- W1992059246 hasAuthorship W1992059246A5015457679 @default.
- W1992059246 hasAuthorship W1992059246A5027632014 @default.
- W1992059246 hasAuthorship W1992059246A5089465265 @default.
- W1992059246 hasConcept C126322002 @default.
- W1992059246 hasConcept C134018914 @default.
- W1992059246 hasConcept C141071460 @default.
- W1992059246 hasConcept C178790620 @default.
- W1992059246 hasConcept C185592680 @default.
- W1992059246 hasConcept C202751555 @default.
- W1992059246 hasConcept C2775844104 @default.
- W1992059246 hasConcept C2776120743 @default.
- W1992059246 hasConcept C2778536324 @default.
- W1992059246 hasConcept C2778815084 @default.
- W1992059246 hasConcept C2778844314 @default.
- W1992059246 hasConcept C2780886150 @default.
- W1992059246 hasConcept C517785266 @default.
- W1992059246 hasConcept C55493867 @default.
- W1992059246 hasConcept C71924100 @default.
- W1992059246 hasConcept C98274493 @default.
- W1992059246 hasConceptScore W1992059246C126322002 @default.
- W1992059246 hasConceptScore W1992059246C134018914 @default.
- W1992059246 hasConceptScore W1992059246C141071460 @default.
- W1992059246 hasConceptScore W1992059246C178790620 @default.
- W1992059246 hasConceptScore W1992059246C185592680 @default.
- W1992059246 hasConceptScore W1992059246C202751555 @default.
- W1992059246 hasConceptScore W1992059246C2775844104 @default.
- W1992059246 hasConceptScore W1992059246C2776120743 @default.
- W1992059246 hasConceptScore W1992059246C2778536324 @default.
- W1992059246 hasConceptScore W1992059246C2778815084 @default.
- W1992059246 hasConceptScore W1992059246C2778844314 @default.
- W1992059246 hasConceptScore W1992059246C2780886150 @default.
- W1992059246 hasConceptScore W1992059246C517785266 @default.
- W1992059246 hasConceptScore W1992059246C55493867 @default.
- W1992059246 hasConceptScore W1992059246C71924100 @default.
- W1992059246 hasConceptScore W1992059246C98274493 @default.
- W1992059246 hasLocation W19920592461 @default.
- W1992059246 hasLocation W19920592462 @default.
- W1992059246 hasOpenAccess W1992059246 @default.
- W1992059246 hasPrimaryLocation W19920592461 @default.
- W1992059246 hasRelatedWork W1992059246 @default.
- W1992059246 hasRelatedWork W1997423683 @default.
- W1992059246 hasRelatedWork W2069000902 @default.
- W1992059246 hasRelatedWork W2075341977 @default.
- W1992059246 hasRelatedWork W2119545386 @default.
- W1992059246 hasRelatedWork W2406657210 @default.
- W1992059246 hasRelatedWork W2414785565 @default.
- W1992059246 hasRelatedWork W2416289301 @default.
- W1992059246 hasRelatedWork W2472885463 @default.
- W1992059246 hasRelatedWork W2762703616 @default.
- W1992059246 hasVolume "53" @default.
- W1992059246 isParatext "false" @default.
- W1992059246 isRetracted "false" @default.
- W1992059246 magId "1992059246" @default.
- W1992059246 workType "article" @default.