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- W1992073111 abstract "The male-specific region of the Y chromosome, the MSY, differentiates the sexes and comprises 95% of the chromosome's length. Here, we report that the MSY is a mosaic of heterochromatic sequences and three classes of euchromatic sequences: X-transposed, X-degenerate and ampliconic. These classes contain all 156 known transcription units, which include 78 protein-coding genes that collectively encode 27 distinct proteins. The X-transposed sequences exhibit 99% identity to the X chromosome. The X-degenerate sequences are remnants of ancient autosomes from which the modern X and Y chromosomes evolved. The ampliconic class includes large regions (about 30% of the MSY euchromatin) where sequence pairs show greater than 99.9% identity, which is maintained by frequent gene conversion (non-reciprocal transfer). The most prominent features here are eight massive palindromes, at least six of which contain testis genes." @default.
- W1992073111 created "2016-06-24" @default.
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- W1992073111 date "1948-05-01" @default.
- W1992073111 modified "2023-09-27" @default.
- W1992073111 title "Quantitative Chromatographic Estimation of α-Amino-Acids" @default.
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- W1992073111 doi "https://doi.org/10.1038/161763a0" @default.
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