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- W1992073996 abstract "For more than ten years the nematode Caenorhabditis elegans has proven to be a valuable model for studies of the host response to various bacterial and fungal pathogens. When exposed to a pathogenic organism, a clear response is elicited in the nematode, which is characterized by specific alterations on the transcriptional and translational levels. Early on, researchers took advantage of the possibility to conduct large-scale investigations of the C. elegans immune response. Multiple studies demonstrated that C. elegans does indeed mount a protective response against invading pathogens, thus rendering this small nematode a very useful and simple host model for the study of innate immunity and host-pathogen interactions. Here, we provide an overview of key aspects of innate immunity in C. elegans revealed by recent whole-genome transcriptomics and proteomics studies of the global response of C. elegans to various bacterial and fungal pathogens." @default.
- W1992073996 created "2016-06-24" @default.
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- W1992073996 creator A5041757990 @default.
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- W1992073996 date "2012-10-01" @default.
- W1992073996 modified "2023-10-03" @default.
- W1992073996 title "Strength in numbers" @default.
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- W1992073996 doi "https://doi.org/10.4161/viru.21906" @default.
- W1992073996 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3524146" @default.
- W1992073996 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23076279" @default.
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