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- W1992095113 abstract "Abstract Extract The nature of the relationship between humoral immunity, characterised by the presence of serum antibodies, and delayed hypersensitivity, demonstrated by skin reactions, was a puzzle to early immunologists. The observation, made in 1945, that delayed hypersensitivity could be transferred from a sensitised to a normal animal by leucocytes but not by serum suggested that these two forms of immunity were separable. Soon after this observation was made a number of neonatal diseases associated with various immune deficiencies were described in children. The clinical features of these diseases and differences in their pathology also suggested a division between humoral and cellular immunity and, furthermore, indicated a role for the thymus in immunity. But it was the fortuitous discovery in 1956 that bursectomized chickens were unable to produce antibody but retained their cellular immunity that first established a definite relationship between a primary lymphoid organ and an immune function. A..." @default.
- W1992095113 created "2016-06-24" @default.
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- W1992095113 date "1984-08-01" @default.
- W1992095113 modified "2023-09-26" @default.
- W1992095113 title "The cellular basis of immunity" @default.
- W1992095113 doi "https://doi.org/10.1080/00480169.1984.35092" @default.
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