FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1992172022> ?p ?o ?g. }

• W1992172022 endingPage "915" @default.
• W1992172022 startingPage "902" @default.
• W1992172022 abstract "ABSTRACT During filamentous fungus development, multinucleated hyphae employ a system for long-range nuclear migration to maintain an equal nuclear density. A decade ago the microtubule motor dynein was shown to play a central role in this process. Previous studies with Ashbya gossypii revealed extensive bidirectional movements and bypassings of nuclei, an autonomous cytoplasmic microtubule (cMT) cytoskeleton emanating from each nucleus, and pulling of nuclei by sliding of cMTs along the cortex. Here, we show that dynein is the sole motor for bidirectional movements and bypassing because these movements are concomitantly decreased in mutants carrying truncations of the dynein heavy-chain DYN1 promoter. The dynactin component Jnm1, the accessory proteins Dyn2 and Ndl1, and the potential dynein cortical anchor Num1 are also involved in the dynamic distribution of nuclei. In their absence, nuclei aggregate to different degrees, whereby the mutants with dense nuclear clusters grow extremely long cMTs. As in budding yeast, we found that dynein is delivered to cMT plus ends, and its activity or processivity is probably controlled by dynactin and Num1. Together with its role in powering nuclear movements, we propose that dynein also plays (directly or indirectly) a role in the control of cMT length. Those combined dynein actions prevent nuclear clustering in A. gossypii and thus reveal a novel cellular role for dynein." @default.
• W1992172022 created "2016-06-24" @default.
• W1992172022 creator A5012297582 @default.
• W1992172022 creator A5040566072 @default.
• W1992172022 creator A5050742440 @default.
• W1992172022 creator A5060376957 @default.
• W1992172022 creator A5082785811 @default.
• W1992172022 creator A5087169514 @default.
• W1992172022 date "2011-07-01" @default.
• W1992172022 modified "2023-09-27" @default.
• W1992172022 title "Clustering of Nuclei in Multinucleated Hyphae Is Prevented by Dynein-Driven Bidirectional Nuclear Movements and Microtubule Growth Control in Ashbya gossypii" @default.
• W1992172022 cites W1835995439 @default.
• W1992172022 cites W1968654429 @default.
• W1992172022 cites W1985627463 @default.
• W1992172022 cites W1986658657 @default.
• W1992172022 cites W1994412820 @default.
• W1992172022 cites W1996888932 @default.
• W1992172022 cites W1999286862 @default.
• W1992172022 cites W2005633093 @default.
• W1992172022 cites W2006598868 @default.
• W1992172022 cites W2008679100 @default.
• W1992172022 cites W2012575511 @default.
• W1992172022 cites W2022999504 @default.
• W1992172022 cites W2023281151 @default.
• W1992172022 cites W2032685738 @default.
• W1992172022 cites W2035156722 @default.
• W1992172022 cites W2044668046 @default.
• W1992172022 cites W2046561940 @default.
• W1992172022 cites W2073921638 @default.
• W1992172022 cites W2077347535 @default.
• W1992172022 cites W2078025643 @default.
• W1992172022 cites W2078146767 @default.
• W1992172022 cites W2097727291 @default.
• W1992172022 cites W2102300724 @default.
• W1992172022 cites W2103406786 @default.
• W1992172022 cites W2115850825 @default.
• W1992172022 cites W2116811981 @default.
• W1992172022 cites W2116905253 @default.
• W1992172022 cites W2128324727 @default.
• W1992172022 cites W2131589174 @default.
• W1992172022 cites W2131662406 @default.
• W1992172022 cites W2133664013 @default.
• W1992172022 cites W2135012523 @default.
• W1992172022 cites W2135607368 @default.
• W1992172022 cites W2136133971 @default.
• W1992172022 cites W2141055054 @default.
• W1992172022 cites W2141497558 @default.
• W1992172022 cites W2143836295 @default.
• W1992172022 cites W2146750095 @default.
• W1992172022 cites W2146831574 @default.
• W1992172022 cites W2149151220 @default.
• W1992172022 cites W2152222390 @default.
• W1992172022 cites W2152965914 @default.
• W1992172022 cites W2160392200 @default.
• W1992172022 cites W2165843409 @default.
• W1992172022 cites W2212598933 @default.
• W1992172022 cites W2253307529 @default.
• W1992172022 doi "https://doi.org/10.1128/ec.05095-11" @default.
• W1992172022 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3147418" @default.
• W1992172022 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21642510" @default.
• W1992172022 hasPublicationYear "2011" @default.
• W1992172022 type Work @default.
• W1992172022 sameAs 1992172022 @default.
• W1992172022 citedByCount "28" @default.
• W1992172022 countsByYear W19921720222012 @default.
• W1992172022 countsByYear W19921720222013 @default.
• W1992172022 countsByYear W19921720222014 @default.
• W1992172022 countsByYear W19921720222015 @default.
• W1992172022 countsByYear W19921720222016 @default.
• W1992172022 countsByYear W19921720222017 @default.
• W1992172022 countsByYear W19921720222018 @default.
• W1992172022 countsByYear W19921720222019 @default.
• W1992172022 countsByYear W19921720222020 @default.
• W1992172022 countsByYear W19921720222021 @default.
• W1992172022 countsByYear W19921720222022 @default.
• W1992172022 countsByYear W19921720222023 @default.
• W1992172022 crossrefType "journal-article" @default.
• W1992172022 hasAuthorship W1992172022A5012297582 @default.
• W1992172022 hasAuthorship W1992172022A5040566072 @default.
• W1992172022 hasAuthorship W1992172022A5050742440 @default.
• W1992172022 hasAuthorship W1992172022A5060376957 @default.
• W1992172022 hasAuthorship W1992172022A5082785811 @default.
• W1992172022 hasAuthorship W1992172022A5087169514 @default.
• W1992172022 hasBestOaLocation W19921720221 @default.
• W1992172022 hasConcept C106987784 @default.
• W1992172022 hasConcept C134729014 @default.
• W1992172022 hasConcept C142669718 @default.
• W1992172022 hasConcept C1491633281 @default.
• W1992172022 hasConcept C20418707 @default.
• W1992172022 hasConcept C54355233 @default.
• W1992172022 hasConcept C86803240 @default.
• W1992172022 hasConcept C93126451 @default.
• W1992172022 hasConcept C95444343 @default.
• W1992172022 hasConceptScore W1992172022C106987784 @default.
• W1992172022 hasConceptScore W1992172022C134729014 @default.
• W1992172022 hasConceptScore W1992172022C142669718 @default.
• W1992172022 hasConceptScore W1992172022C1491633281 @default.
• W1992172022 hasConceptScore W1992172022C20418707 @default.

• next