FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1992175021> ?p ?o ?g. }

• W1992175021 endingPage "253" @default.
• W1992175021 startingPage "246" @default.
• W1992175021 abstract "Despite significant advances in management, Paget disease remains an enigmatic disorder. There are no animal models, and while its end result – a focal disorder of accelerated bone turnover – is easily recognized, the causes and evolution of the disorder remain uncertain. Recent evidence strongly implicates both genetic and environmental factors in its etiology. The authors consider some of the unresolved questions surrounding Paget disease, including the attenuating prevalence and severity of the disease; how these observations might be reconciled with an apparently highly penetrant genetic susceptibility; what the putative environmental triggers of Paget disease might be; and what relapse after treatment tells us. Most observations seem to fit best with the idea that Paget disease behaves as a multifocal benign neoplasm. Despite significant advances in management, Paget disease remains an enigmatic disorder. There are no animal models, and while its end result – a focal disorder of accelerated bone turnover – is easily recognized, the causes and evolution of the disorder remain uncertain. Recent evidence strongly implicates both genetic and environmental factors in its etiology. The authors consider some of the unresolved questions surrounding Paget disease, including the attenuating prevalence and severity of the disease; how these observations might be reconciled with an apparently highly penetrant genetic susceptibility; what the putative environmental triggers of Paget disease might be; and what relapse after treatment tells us. Most observations seem to fit best with the idea that Paget disease behaves as a multifocal benign neoplasm." @default.
• W1992175021 created "2016-06-24" @default.
• W1992175021 creator A5068597827 @default.
• W1992175021 creator A5090695901 @default.
• W1992175021 date "2008-09-01" @default.
• W1992175021 modified "2023-10-03" @default.
• W1992175021 title "Paget disease of bone" @default.
• W1992175021 cites W1855737037 @default.
• W1992175021 cites W1971365252 @default.
• W1992175021 cites W1977478421 @default.
• W1992175021 cites W1978652964 @default.
• W1992175021 cites W1995363738 @default.
• W1992175021 cites W1995426783 @default.
• W1992175021 cites W1998277547 @default.
• W1992175021 cites W1999680191 @default.
• W1992175021 cites W2002428055 @default.
• W1992175021 cites W2002458271 @default.
• W1992175021 cites W2004060405 @default.
• W1992175021 cites W2008899984 @default.
• W1992175021 cites W2009267723 @default.
• W1992175021 cites W2010622800 @default.
• W1992175021 cites W2011308707 @default.
• W1992175021 cites W2011378997 @default.
• W1992175021 cites W2011683420 @default.
• W1992175021 cites W2015069333 @default.
• W1992175021 cites W2016084217 @default.
• W1992175021 cites W2016415830 @default.
• W1992175021 cites W2020720412 @default.
• W1992175021 cites W2024417809 @default.
• W1992175021 cites W2032311243 @default.
• W1992175021 cites W2039205187 @default.
• W1992175021 cites W2041703759 @default.
• W1992175021 cites W2045022243 @default.
• W1992175021 cites W2045935252 @default.
• W1992175021 cites W2053175087 @default.
• W1992175021 cites W2055169741 @default.
• W1992175021 cites W2057905673 @default.
• W1992175021 cites W2058683026 @default.
• W1992175021 cites W2059557215 @default.
• W1992175021 cites W2062620118 @default.
• W1992175021 cites W2064496724 @default.
• W1992175021 cites W2068341194 @default.
• W1992175021 cites W2069134913 @default.
• W1992175021 cites W2075437829 @default.
• W1992175021 cites W2081669270 @default.
• W1992175021 cites W2084990335 @default.
• W1992175021 cites W2086325838 @default.
• W1992175021 cites W2087054224 @default.
• W1992175021 cites W2098273098 @default.
• W1992175021 cites W2104817968 @default.
• W1992175021 cites W2106679696 @default.
• W1992175021 cites W2108471060 @default.
• W1992175021 cites W2109079739 @default.
• W1992175021 cites W2116217447 @default.
• W1992175021 cites W2116807721 @default.
• W1992175021 cites W2132675666 @default.
• W1992175021 cites W2341313852 @default.
• W1992175021 doi "https://doi.org/10.1016/j.tem.2008.06.001" @default.
• W1992175021 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18691901" @default.
• W1992175021 hasPublicationYear "2008" @default.
• W1992175021 type Work @default.
• W1992175021 sameAs 1992175021 @default.
• W1992175021 citedByCount "51" @default.
• W1992175021 countsByYear W19921750212012 @default.
• W1992175021 countsByYear W19921750212013 @default.
• W1992175021 countsByYear W19921750212014 @default.
• W1992175021 countsByYear W19921750212015 @default.
• W1992175021 countsByYear W19921750212016 @default.
• W1992175021 countsByYear W19921750212018 @default.
• W1992175021 countsByYear W19921750212019 @default.
• W1992175021 countsByYear W19921750212020 @default.
• W1992175021 countsByYear W19921750212023 @default.
• W1992175021 crossrefType "journal-article" @default.
• W1992175021 hasAuthorship W1992175021A5068597827 @default.
• W1992175021 hasAuthorship W1992175021A5090695901 @default.
• W1992175021 hasConcept C137627325 @default.
• W1992175021 hasConcept C142724271 @default.
• W1992175021 hasConcept C2778908642 @default.
• W1992175021 hasConcept C2779134260 @default.
• W1992175021 hasConcept C67636389 @default.
• W1992175021 hasConcept C71924100 @default.
• W1992175021 hasConceptScore W1992175021C137627325 @default.
• W1992175021 hasConceptScore W1992175021C142724271 @default.
• W1992175021 hasConceptScore W1992175021C2778908642 @default.
• W1992175021 hasConceptScore W1992175021C2779134260 @default.
• W1992175021 hasConceptScore W1992175021C67636389 @default.
• W1992175021 hasConceptScore W1992175021C71924100 @default.
• W1992175021 hasIssue "7" @default.
• W1992175021 hasLocation W19921750211 @default.
• W1992175021 hasLocation W19921750212 @default.
• W1992175021 hasOpenAccess W1992175021 @default.
• W1992175021 hasPrimaryLocation W19921750211 @default.
• W1992175021 hasRelatedWork W1500724515 @default.
• W1992175021 hasRelatedWork W2042846546 @default.
• W1992175021 hasRelatedWork W2079992490 @default.
• W1992175021 hasRelatedWork W2119488348 @default.
• W1992175021 hasRelatedWork W2412965123 @default.
• W1992175021 hasRelatedWork W2415255741 @default.

• next