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• W1992180888 abstract "<i>Streptomyces coelicolor</i> A3(2) is an extensively studied model organism for the genetic studies of Streptomycetes – a genus known for the production of a vast number of bioactive compounds and complex regulatory networks controlling morphological differentiation and secondary metabolites production. We present the discovery of a presumptive product of the Cpk polyketide synthase. We have found that on the rich medium without glucose <i>S. coelicolor</i> A3(2) produces a yellow compound secreted into the medium. We have proved by complementation that production of the observed yellow pigment is dependent on <i>cpk</i> gene cluster previously described as cryptic type I polyketide synthase cluster. The pigment production depends on the medium composition, does not occur in the presence of glucose, and requires high density of spore suspension used for inoculation." @default.
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• W1992180888 date "2010-01-01" @default.
• W1992180888 modified "2023-09-23" @default.
• W1992180888 title "<i>Streptomyces coelicolor</i> A3(2) Produces a New Yellow Pigment Associated with the Polyketide Synthase Cpk" @default.
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• W1992180888 doi "https://doi.org/10.1159/000321501" @default.
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