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- W1992232854 abstract "Therapies for hepatitis B virus (HBV) have continued to evolve, and new therapies for hepatitis C virus (HCV) will soon be available in clinical practice. These medications for hepatitis C will mark the first time that direct antivirals that target HCV functions have been used. When such drugs are used as single agents, previously existing mutants with reduced susceptibility to them are rapidly selected. The relationship between these drug-resistant mutants and “wild-type” virus is unclear, but resistant strains likely have the potential to maintain the progression of liver disease despite successful treatment of “wild-type” virus. Resistant HBV and now HCV are already a clinical problem. The same issue was recognized very early in the development of therapy against HIV, with azidothymidine-resistant mutants detected within the first weeks of therapy. Clinical investigation and a progressive understanding of the pathogenesis of the disease overcame this challenge and led to the substantial and durable benefits of antiretroviral therapy that are evident today. To bring experts from the fields of HIV and viral hepatitis virology and therapy together for interactive discussions about how to apply the lessons from HIV to the further development of viral hepatitis therapy, the American Association for the Study of Liver Diseases held a single-topic conference entitled “Viral Hepatitis Therapy: Lessons to be Learned From HIV” on 24–26 July 2008. This article summarizes that conference." @default.
- W1992232854 created "2016-06-24" @default.
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- W1992232854 date "2010-05-01" @default.
- W1992232854 modified "2023-10-18" @default.
- W1992232854 title "Lessons From HIV Therapy Applied to Viral Hepatitis Therapy: Summary of a Workshop" @default.
- W1992232854 cites W1497170016 @default.
- W1992232854 cites W1515293536 @default.
- W1992232854 cites W1964963193 @default.
- W1992232854 cites W1966668708 @default.
- W1992232854 cites W1969835589 @default.
- W1992232854 cites W1978363938 @default.
- W1992232854 cites W1979174109 @default.
- W1992232854 cites W1981170530 @default.
- W1992232854 cites W1981526509 @default.
- W1992232854 cites W1982433898 @default.
- W1992232854 cites W1983113514 @default.
- W1992232854 cites W1985891965 @default.
- W1992232854 cites W1986283951 @default.
- W1992232854 cites W1988242030 @default.
- W1992232854 cites W1992239172 @default.
- W1992232854 cites W1993484328 @default.
- W1992232854 cites W1995565071 @default.
- W1992232854 cites W1996434966 @default.
- W1992232854 cites W1999376769 @default.
- W1992232854 cites W2003579943 @default.
- W1992232854 cites W2006545772 @default.
- W1992232854 cites W2007134915 @default.
- W1992232854 cites W2014616917 @default.
- W1992232854 cites W2019519338 @default.
- W1992232854 cites W2019672317 @default.
- W1992232854 cites W2022853819 @default.
- W1992232854 cites W2027545702 @default.
- W1992232854 cites W2041886898 @default.
- W1992232854 cites W2042094643 @default.
- W1992232854 cites W2042284834 @default.
- W1992232854 cites W2043519223 @default.
- W1992232854 cites W2044193462 @default.
- W1992232854 cites W2047208492 @default.
- W1992232854 cites W2050571266 @default.
- W1992232854 cites W2053100601 @default.
- W1992232854 cites W2063783484 @default.
- W1992232854 cites W2064059889 @default.
- W1992232854 cites W2064461416 @default.
- W1992232854 cites W2072291558 @default.
- W1992232854 cites W2085250492 @default.
- W1992232854 cites W2088221871 @default.
- W1992232854 cites W2088234365 @default.
- W1992232854 cites W2091287215 @default.
- W1992232854 cites W2094688618 @default.
- W1992232854 cites W2094705613 @default.
- W1992232854 cites W2095444472 @default.
- W1992232854 cites W2097073538 @default.
- W1992232854 cites W2099843722 @default.
- W1992232854 cites W2100797437 @default.
- W1992232854 cites W2101516953 @default.
- W1992232854 cites W2103185551 @default.
- W1992232854 cites W2107057287 @default.
- W1992232854 cites W2111934155 @default.
- W1992232854 cites W2112876622 @default.
- W1992232854 cites W2114392718 @default.
- W1992232854 cites W2115869094 @default.
- W1992232854 cites W2116873531 @default.
- W1992232854 cites W2119888523 @default.
- W1992232854 cites W2120915945 @default.
- W1992232854 cites W2121595515 @default.
- W1992232854 cites W2122280827 @default.
- W1992232854 cites W2122858451 @default.
- W1992232854 cites W2126124947 @default.
- W1992232854 cites W2127685726 @default.
- W1992232854 cites W2131362526 @default.
- W1992232854 cites W2133758885 @default.
- W1992232854 cites W2135950944 @default.
- W1992232854 cites W2140880940 @default.
- W1992232854 cites W2141460271 @default.
- W1992232854 cites W2142876072 @default.
- W1992232854 cites W2145899386 @default.
- W1992232854 cites W2146397496 @default.
- W1992232854 cites W2147314139 @default.
- W1992232854 cites W2151898297 @default.
- W1992232854 cites W2156015715 @default.
- W1992232854 cites W2156027719 @default.
- W1992232854 cites W2160648249 @default.
- W1992232854 cites W2163818375 @default.
- W1992232854 cites W2164704571 @default.
- W1992232854 cites W2166075101 @default.
- W1992232854 cites W2168736565 @default.
- W1992232854 cites W2168912424 @default.
- W1992232854 cites W2170919492 @default.
- W1992232854 cites W2171470373 @default.
- W1992232854 cites W2318289184 @default.