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- W1992234358 abstract "Phenylketonuria (PKU) is a highly deleterious recessive pathology of amino acid metabolism in which estimated allele frequencies may reach as high as 1·0 to 1·5% in some populations. The high incidence of the allele and the deleterious condition of the homozygote suggest that there may be, heterozygote advantage. If European samples are divided into Celtic and non-Celtic continental European, the estimated heterozygote incidence correlates significantly with available midwinter sunlight (Celtic r=−0·80; p" @default.
- W1992234358 created "2016-06-24" @default.
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- W1992234358 date "1978-03-01" @default.
- W1992234358 modified "2023-09-27" @default.
- W1992234358 title "Phenylketonuria: A balanced polymorphism in Europe?" @default.
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- W1992234358 doi "https://doi.org/10.1016/s0047-2484(78)80114-6" @default.
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