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- W1992270198 abstract "The dissolution rate of a batch of drug substance is related to its intrinsic dissolution rate and particle size distribution. For dissolution purposes, the volume/surface weighted mean diameter (dvs) appears to be the best descriptor of a batchKnowledge of the intrinsic dissolution rate of a compound allows the formulator to set a particle size specification for that compound. This ensures batch to batch consistency of in vitro dissolution performance and affords a high degree of assurance that bioavailability will be maximisedExamples cited are phenacetin, nitrofurantoin, griseofulvin, methylprednisolone and cromakalim" @default.
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- W1992270198 date "1989-01-01" @default.
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- W1992270198 title "Volume/Surface Weighted Mean Diameter as an Indicator of Dissolution Rate" @default.
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- W1992270198 doi "https://doi.org/10.3109/03639048909052541" @default.
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