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• W1992300757 abstract "The effect of atherosclerosis on alveolar bone blood flow and several periodontal tissue parameters was examined in the rhesus monkey. Five adult monkeys were maintained on an atherogenic diet for 54 months and the remaining five animals were fed a normal diet. Prior to death, radiolabelled microspheres were used to measure bone blood flow in the posterior regions of maxilla and mandible. Tracings were made of mesio-distal histological sections through the premolar and molar teeth in each jaw and measurements were taken of bone area, crestal bone height, level of epithelial attachment, and number of osteoclast nuclei. The atherosclerotic monkeys showed a significant decrease in all these parameters compared to controls. Blood flow was significantly lower in the maxilla of atherosclerotic animals, and there was a significant correlation in both groups between reduced blood flow and loss of crestal bone; in the atherosclerotic monkeys reduced blood flow was also significantly correlated with a more apical junctional epithelia. It is possible that reduced blood flow such as that associated with atherosclerotic disease may render the periodontal tissues more susceptible to destruction by etiological agents such as plaque." @default.
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• W1992300757 date "1985-09-01" @default.
• W1992300757 modified "2023-10-18" @default.
• W1992300757 title "Blood flow and periodontal destruction in normal and atherosclerotic rhesus monkeys" @default.
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• W1992300757 doi "https://doi.org/10.1111/j.1600-0765.1985.tb00825.x" @default.
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