FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1992307368> ?p ?o ?g. }

• W1992307368 endingPage "359" @default.
• W1992307368 startingPage "357" @default.
• W1992307368 abstract "We have demonstrated previously that oxygen-derived free radicals are important mediators of tissue injury following ischemia (total venous occlusion) and reperfusion in small (3 cm X 6 cm) island skin flaps in rats. In this study, we evaluated extension of this concept to regional ischemia in large (8 cm X 8 cm) acute island skin flaps which were constructed to exceed their sole blood supply via unilateral inferior epigastric vessels. Under normal (control) circumstances, a significant portion of the flap would undergo necrosis at the periphery, mimicking the corresponding clinical situation. Blocking the generation of superoxide radicals from xanthine oxidase with a single dose of allopurinol prior to flap elevation significantly improved the area of flap viability from 34 +/- 12% to 57 +/- 6% (p less than 0.01) in the random portion of the flap, contralateral to the source of blood supply. Similarly, the detoxification of superoxide radicals with a single dose of superoxide dismutase improved viability from 41 +/- 6% to 58 +/- 7% (p less than 0.01). Similar results were obtained when either of these agents were administered 60 minutes after flap elevation. These findings suggest that oxygen-derived free radicals play an important role in the development of tissue necrosis in the critical transition zone between well-vascularized and devascularized skin." @default.
• W1992307368 created "2016-06-24" @default.
• W1992307368 creator A5052335994 @default.
• W1992307368 creator A5052823111 @default.
• W1992307368 creator A5053626517 @default.
• W1992307368 creator A5075130234 @default.
• W1992307368 date "1985-03-01" @default.
• W1992307368 modified "2023-10-18" @default.
• W1992307368 title "Effects of Superoxide Dismutase and Allopurinol on the Survival of Acute Island Skin Flaps" @default.
• W1992307368 cites W1522676079 @default.
• W1992307368 cites W153758560 @default.
• W1992307368 cites W195217094 @default.
• W1992307368 cites W1983634320 @default.
• W1992307368 cites W1991327408 @default.
• W1992307368 cites W2004099545 @default.
• W1992307368 cites W2005666696 @default.
• W1992307368 cites W2017226870 @default.
• W1992307368 cites W2019625812 @default.
• W1992307368 cites W2032357352 @default.
• W1992307368 cites W2039793575 @default.
• W1992307368 cites W2052736042 @default.
• W1992307368 cites W2053586809 @default.
• W1992307368 cites W2060221232 @default.
• W1992307368 cites W2061826995 @default.
• W1992307368 cites W2080754538 @default.
• W1992307368 cites W2318054838 @default.
• W1992307368 cites W2328085879 @default.
• W1992307368 doi "https://doi.org/10.1097/00000658-198503000-00018" @default.
• W1992307368 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1250680" @default.
• W1992307368 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3977440" @default.
• W1992307368 hasPublicationYear "1985" @default.
• W1992307368 type Work @default.
• W1992307368 sameAs 1992307368 @default.
• W1992307368 citedByCount "126" @default.
• W1992307368 countsByYear W19923073682012 @default.
• W1992307368 countsByYear W19923073682013 @default.
• W1992307368 countsByYear W19923073682014 @default.
• W1992307368 countsByYear W19923073682015 @default.
• W1992307368 countsByYear W19923073682016 @default.
• W1992307368 countsByYear W19923073682017 @default.
• W1992307368 countsByYear W19923073682018 @default.
• W1992307368 countsByYear W19923073682019 @default.
• W1992307368 countsByYear W19923073682021 @default.
• W1992307368 countsByYear W19923073682022 @default.
• W1992307368 crossrefType "journal-article" @default.
• W1992307368 hasAuthorship W1992307368A5052335994 @default.
• W1992307368 hasAuthorship W1992307368A5052823111 @default.
• W1992307368 hasAuthorship W1992307368A5053626517 @default.
• W1992307368 hasAuthorship W1992307368A5075130234 @default.
• W1992307368 hasBestOaLocation W19923073682 @default.
• W1992307368 hasConcept C126322002 @default.
• W1992307368 hasConcept C139066938 @default.
• W1992307368 hasConcept C141071460 @default.
• W1992307368 hasConcept C181199279 @default.
• W1992307368 hasConcept C185592680 @default.
• W1992307368 hasConcept C2775838275 @default.
• W1992307368 hasConcept C2776151105 @default.
• W1992307368 hasConcept C2778102346 @default.
• W1992307368 hasConcept C2780261098 @default.
• W1992307368 hasConcept C2780795997 @default.
• W1992307368 hasConcept C42219234 @default.
• W1992307368 hasConcept C503630168 @default.
• W1992307368 hasConcept C541997718 @default.
• W1992307368 hasConcept C55493867 @default.
• W1992307368 hasConcept C71924100 @default.
• W1992307368 hasConceptScore W1992307368C126322002 @default.
• W1992307368 hasConceptScore W1992307368C139066938 @default.
• W1992307368 hasConceptScore W1992307368C141071460 @default.
• W1992307368 hasConceptScore W1992307368C181199279 @default.
• W1992307368 hasConceptScore W1992307368C185592680 @default.
• W1992307368 hasConceptScore W1992307368C2775838275 @default.
• W1992307368 hasConceptScore W1992307368C2776151105 @default.
• W1992307368 hasConceptScore W1992307368C2778102346 @default.
• W1992307368 hasConceptScore W1992307368C2780261098 @default.
• W1992307368 hasConceptScore W1992307368C2780795997 @default.
• W1992307368 hasConceptScore W1992307368C42219234 @default.
• W1992307368 hasConceptScore W1992307368C503630168 @default.
• W1992307368 hasConceptScore W1992307368C541997718 @default.
• W1992307368 hasConceptScore W1992307368C55493867 @default.
• W1992307368 hasConceptScore W1992307368C71924100 @default.
• W1992307368 hasIssue "3" @default.
• W1992307368 hasLocation W19923073681 @default.
• W1992307368 hasLocation W19923073682 @default.
• W1992307368 hasLocation W19923073683 @default.
• W1992307368 hasOpenAccess W1992307368 @default.
• W1992307368 hasPrimaryLocation W19923073681 @default.
• W1992307368 hasRelatedWork W1551913643 @default.
• W1992307368 hasRelatedWork W2035837632 @default.
• W1992307368 hasRelatedWork W2042147930 @default.
• W1992307368 hasRelatedWork W2043350581 @default.
• W1992307368 hasRelatedWork W2054626651 @default.
• W1992307368 hasRelatedWork W2094102798 @default.
• W1992307368 hasRelatedWork W2209623208 @default.
• W1992307368 hasRelatedWork W2310738799 @default.
• W1992307368 hasRelatedWork W2413585276 @default.
• W1992307368 hasRelatedWork W2418281073 @default.
• W1992307368 hasVolume "201" @default.
• W1992307368 isParatext "false" @default.

• next